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Experimental study for the bypass of the right heart (Fontan procedure) Evaluation of the bidirectional cavopulmonary connection for Fontan Procedure

Experimental study for the bypass of the right heart (Fontan procedure) Evaluation of the bidirectional cavopulmonary connection for Fontan Procedure
右心搭桥术(Fontan 手术)的实验研究 Fontan 手术双向腔肺连接的评估
批准号:
01480345
负责人:
NAITO Yasuaki
金额:
$2.37万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for General Scientific Research (B)
财政年份:
1989
资助国家:
日本
项目状态:
已结题
起止时间:
1989 至 1990

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中文摘要
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英文摘要
A hepatomegaly and arrhythmias are often induced by high light atrial pressure after right atrium-pulmonary artery bypass (so-called Fontan procedure).Clinically, long-term benefit that these complications are reduced by the bidirectional cavopulmonary shunt in conjunction with Fontan procedure has been demonstrated. However, the mechanism of reducing right atrial load by the bidirectional cavopulmonary shunt is unknown.Therefore, the effects of this operation on hemodynamics and light atrium were studied.Four anesthetized dogs were underwent both a Fontan procedure with closure of tricuspid valve and a bidirectional cavopulmonary shunt. All dogs kept normal sinus rhythm.There were no statistical differences between only a Fontan procedure (bidirectional cavopulmonary shunt closed) and a Fontan procedure with bidirectional cavopulmonary shunt in heart rate (137<plus-minus>22 versus 136<plus-minus>23 bpm), cardiac output (O. 95<plus-minus>0.20 versus 0.91<plus-minus>0.26 l/min), mean blood pressure (37.0<plus-minus>9.0 versus 34.8<plus-minus>7.6 mmHg), Ieft atrial pressure (5.7<plus-minus>4.3 versus 4.9<plus-minus>4.1 mmHg) superior vena caval pressure (14.9<plus-minus>2.7 versus 15.1<plus-minus>2.9 mmHg) and right atrial pressure (16.6<plus-minus>4.0 versus 16There was a significant difference in right atrial myocardial length(100 versus 97.0<plus-minus>1.8%) (p<0.05This result shows that a bidirectional cavopuhnonary shunt in conjunction with a Fontan procedure decreases a right atrial muscle stress. This may improve postoperative hepatomegaly and arrliythmias.
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Physicochemical study on single living budding yeast cells by in vivo time- and space-resolved Raman spectroscopy
  • 批准号:
    19850022
  • 项目类别:
    Grant-in-Aid for Young Scientists (Start-up)
  • 资助金额:
    $1.95万
  • 财政年份:
    2007
  • 负责人:
    NAITO Yasuaki
  • 依托单位:
Influence of ischemia and reperfusion on plasma endothelin -1 and endothelin -1 binding sites in pulmonary vasculature.
  • 批准号:
    09671390
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 资助金额:
    $1.28万
  • 财政年份:
    1997
  • 负责人:
    NAITO Yasuaki
  • 依托单位: