Production of new intraoral scanning ultrasonic prove and application to tumor invasion

本研究旨在制造一种新的口腔内探针，并阐明肿瘤厚度与转移率之间的关系。使用10 mhz线性阵列换能器进行实时b扫描US检查（SSD-630; Aloka）。过去三年（1991-1993年）取得的成果如下：正常舌缘回声图分为两层或三层，分别为舌粘膜层、黏膜固有层、肌肉层。舌癌的超声图表现为三角形或梯形的肿瘤形状，其底部为粘膜表面，顶部为肌肉。肿瘤的超声图显示低回声病变与高回声肌肉层形成对比。病理上认为低回声病变为肿瘤细胞、结缔组织、血管和角化组织。肿瘤超声图的边界反映了肿瘤末端与舌肌之间的组织结构。转移病例往往形成较深的肿瘤厚度。在治疗中表现出转移淋巴结的病例明显比那些随后发展为病理转移的病例更深。

This study was designed to produce a new intraoral probe and to clarify the relationship between tumor thickness and metastatic rate. Real-time, B-scan US examinations (SSD-630 ; Aloka) were performed by using a 10-MHz linear array transducer. The results were achieved over the past 3 years (1991-1993) were the following :1. Echogram of the margin of normal tongue constituted two or three layrs, the layrs of which were considered to be tunica mucosa linguae, lamina propri a mucosae, muscle layr.2. Echogram of tongue cancer demonstrated triangular or trapezoidal tumor shape, with its base being the surface of the mucous membrane and its spex the muscle. Echogram of the cancers indicated hypoechoic lesions in contrast with a hyperechoic muscle layr.3. The hypoechoic lesions (= "tumor" ) were pathologically considered to be tumor cells and connective tissue, vessels and keratinized tissue.4. The boundary of the tumor echogram reflected the tissue structure between the end of the tumor and tongue muscle.5. The metastatic cases tended to create a deeper tumor thickness.6. The cases exhibiting metastatic nodes at the treatment were significantly deeper than those that had subsequently developed metastasis pathologicaly.