Development of non-iodinated, non ionic, water-soluble metal based compounds for clinical administration as radiographic contrast media.

开发用于临床施用的非碘化、非离子、水溶性金属化合物作为放射照相造影剂。

• 批准号: DP0557989
• 负责人: Prof Peter Junk
• 金额: $ 20.78万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2005
• 资助国家: 澳大利亚
• 起止时间: 2005-04-01 至 2008-07-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0557989
• 关键词: Development; non; iodinated; ionic; water

Every year Australia spends more than $50 million on importing radiographic contrast media, in an international market worth more than $1 billion pa. Existing iodine based agents, which currently cause major adverse reactions in 1% of the population, could be replaced by new metal based imaging media which provide both enhanced contrast and greater patient safety and comfort. Even a small fraction of the international market would generate millions of dollars in overseas income from a range of potential sources, including licensing/royalties to export by a local start-up company, and expansion of rare earth mining in Australia.

澳大利亚每年花费超过5000万美元进口放射造影剂，国际市场价值超过10亿美元。现有的碘基试剂目前在1%的人群中引起主要不良反应，可以被新的金属基成像介质所取代，这些介质可以提供增强的对比度和更大的患者安全性和舒适度。即使是国际市场的一小部分，也会从一系列潜在来源产生数百万美元的海外收入，包括当地初创公司的出口许可证/特许权使用费，以及在澳大利亚扩大稀土开采。