The effect of gelanicals on viral infectious desease in senium

凝胶类药物对老年人病毒感染性疾病的作用

• 批准号: 05454235
• 负责人: UEBA Noboru
• 金额: $ 3.46万
• 依托单位: Osaka Prefectural Institute of Public Health
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for General Scientific Research (B)
• 财政年份: 1993
• 资助国家: 日本
• 起止时间: 1993 至 1995
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-05454235/
• 关键词: Antibody producition; Mouse; Prescribed herbal medicine; Phylaxis; Senile; 高齢期

Research into the effect of herbal medication on the declined immune system of the old aged was carried out using about 140 different isolated herbal medicines and several types of prescribed Chinese herbal medicine. It was clear that ogi, ginseng, angelica root and about ten other isolated herbal medicines, activated the immune system in the old aged. And of the prescribed Chinese herbal medicine, hochuekki-to, juzentaiho-to, and maobushisaishinn-to had effect. We made an investigation to see if they can actually improve the phylaxis function in the old aged with the viral infection. It was clear that angelica root, ogi and ginseng improved the phylaxis function against infection of Japanese encephalitis virus. Maobushisaishinn-to had effect against infection of influenza virus.

为探讨中药对老年人免疫功能减退的影响，采用约140种不同的中草药和几种处方中草药对老年人免疫功能衰退进行了研究。显然，OGI、人参、当归等大约十种孤立的中草药，可以激活老年人的免疫系统。在处方的中草药中，Hochuekki-to，juzentaiho-to，mabushisaisisinto-to起作用。我们做了一项调查，看看他们是否真的能改善患有病毒感染的老年人的预防功能。结果表明，当归、当归、人参对乙型脑炎病毒感染有明显的保护作用。毛不什塞心-TO具有抗流感病毒感染的作用。

项目成果

Yasuhiro TAKAGI,Akiko MAEDA,Noboru UEBA,Natsumi HIGASHI,Hirohiko YAMAMURA,Yoshiki NUNOURA: "Effect of mao-bushi-saishin-to, a traditional herb medicine, on influenza virus infection in aged mouse" Biomedical Gerontology. 19. 120 (1995)

Yasuhiro TAKAGI、Akiko MAEDA、Noboru UEBA、Natsumi HIGASHI、Hirohiko YAMAMURA、Yoshiki NUNOURA：“传统草药 mao-bushi-saishin-to 对老年小鼠流感病毒感染的影响”生物医学老年学。

Keiji KAJIMURA,Yasuhiro TAKAGI,Mayumi MIMURA,Noboru UEBA,Kaitsuhiro YAMASAKI,Yoshikazu SAKAGAMI,Hiroshi YOKOYAMA and Kaisuke YONEDA: "Pharmacological Quality of Astragali Radix : the Effect on Atibody Production in vitro" Natural Medicines. 51 (1) (in pre

Keiji KAJIMURA、Yasuhiro TAKAGI、Mayumi MIMURA、Noboru UEBA、Kaitsuhiro YAMASAKI、Yoshikazu SAKAGAMI、Hiroshi YOKOYAMA 和 Kaisuke YONEDA：“黄芪的药理质量：对体外抗体产生的影响”天然药物。

Keiji KAJIMURA: "Protective effect of Astragali Radix by intraperitoneal injection against" Biological Pharmaceutical Bulletin. 19. 855-859 (1996)

梶村敬二：《黄芪腹腔注射对人体的保护作用》生物制药通报。

Yasuhiro TAKAGI: "Effect of mao-bushi-saishin-to on the primary antibody response in mice" J.Traditional Medicines. 13. 94-99 (1996)

Yasuhiro TAKAGI：“mao-bushi-saishin-to 对小鼠初级抗体反应的影响”J.Traditional Medicines。

Keiji Kajimura et al: "Pharmacological Quality of Astragali Radix : the Effect on Atibody Production" Natural Medicines. 51. in press (1997)

Keiji Kajimura 等人：“黄芪的药理质量：对抗体产生的影响”天然药物。