Development of a Membrane Oxygenator Combined with Pumping Function

结合泵送功能的膜氧合器的研制

• 批准号: 05671132
• 负责人: TOMINAGA Seiichi
• 金额: $ 1.34万
• 依托单位: Kitasato University School of Medicine
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for General Scientific Research (C)
• 财政年份: 1993
• 资助国家: 日本
• 起止时间: 1993 至 1994
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-05671132/
• 关键词: Membrane Oxygenator; Extracorporeal Circulation; Pumping Function; Silicone Tube; 体外循環; 気体圧駆動膜型人工心肺; ポンピング機能を有する人工肺; 人工肺

A new membrane oxygenator combined with pumping function was designed to shorten the extracorporeal circulation circuit and to increase the efficiency of oxygenation. At a polycarbonate cylinder, 1500 silicone tubes were bundled and packed among elastic silicone filler. In both inflow and outflow sides of the cylinder, ball valves were equipped.The total available area of the membrane was 7.4*10^<-2> m^2. The membrane was pneumatically driven with a reciprocating pump in performance tests, in which 100% oxygen circulated in the gas side. The mock test shows that the partial pressure of oxygen increases from 0.7*10^4 Pa at the inlet to 7*10^4 Pa at the outlet of the oxygenator when 1.7*10^<-6> m^3 s^<-1> saline solution is pumped.

设计了一种结合泵送功能的新型膜式氧合器，缩短了体外循环回路，提高了氧合效率。在聚碳酸酯圆筒中，1500 根硅胶管被捆扎并填充在弹性硅胶填料中。在圆筒的流入侧和流出侧均设有球阀。膜的总可用面积为7.4×10^-2m^2。在性能测试中，膜采用往复泵气动驱动，其中100%氧气在气体侧循环。模拟测试表明，泵送1.7*10^<-6> m^3 s^<-1> 盐水溶液时，氧分压从入口处的0.7*10^4 Pa增加到出口处的7*10^4 Pa。

项目成果

Shigehiro HASHIMOTO: "Development of a Membrane Oxygenator Combined with Pumping Function" The 6th Bioengineering Division Conference '94 (The Japan Society of Mechanical Engineers). 940-35. 82-84 (1994)

Shigehiro HASHIMOTO：“结合泵送功能的膜氧合器的开发”第 6 届生物工程分部会议 94（日本机械工程师学会）。

橋本成広: "気体圧駆動膜型人工心肺の開発" 日本機械学会論文集. 60. 491-495 (1994)

Shigehiro Hashimoto：“气动驱动膜式心肺机的开发”日本机械工程师学会汇刊 60. 491-495 (1994)。

橋本成広: "気体圧駆動膜型人工肺の開発" 日本機械学会論文集. 60(570). 491-495 (1993)

Shigehiro Hashimoto：“气动膜氧合器的开发”，日本机械工程师学会汇刊 60(570) (1993)。

橋本成広: "気体圧駆動膜型人工心肺の開発" 日本機械学会論文集. 60(570). 491-495 (1993)

Shigehiro Hashimoto：“气动膜式心肺机的开发”，日本机械工程师学会会刊 60(570) 491-495 (1993)。

橋本成広: "ポンプ兼用型膜型人工肺の開発" 第6回バイオエンジニアリング学術講演会講演論文集. 940-35. 82-84 (1994)

Shigehiro Hashimoto：“开发兼作泵的膜氧合器”第六届生物工程学术会议记录 940-35 (1994)。