Study on the Mechanism of Subgingival Calculus Formation

龈下牙石形成机制的研究

• 批准号: 05671587
• 负责人: MAITA Eikichi
• 金额: $ 1.34万
• 依托单位: TOHOKU UNIVERSITY
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for General Scientific Research (C)
• 财政年份: 1993
• 资助国家: 日本
• 起止时间: 1993 至 1994
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-05671587/
• 关键词: Periodonted Pocket; pH; Calculus; ALP; GCF; Polyamines; 歯石; ALP; 歯肉縁下歯石; ALP活性

Beetrode ^R and antimony electrodes were used in this investigation. With increase the calculus index of 0,1,2 in the intrapocket pH slightly shifted without significantly (r=0.21). In cotrast, at the calculus index of 3 the pH value decreased. The significant relationship betweem pocket depth and pocket pH was not shown in 4 healthy subjects. The pH in the pocket depth 1,2,3 mm ranged widely pH 5.8 to pH 7.8. And, the pocket depth of 4mm ranged pH 6.5 to pH 7.4. However, in the ocasion of 5 per iodontal patients, the relationship between pocket depth and pocket pH showed positive linear relation (r=0.54). The pH in the periodontal pocket in the patients ranged more alkaline than the healthy subjects.The poliamiens in saliva and GCF in the patients were analized. The amounts of poliamines in GCF were significantly greater than that in saliva. It has been reported that the poliamines are not detected in pure saliva. So, the poliamines in whole saliva detected in the present study must be leaked from gingival sulcus. Furthermore, the positive relationship was observed between the amount of poliamines and the pH in the pocket.The activities of ALP in GCF (533.2<plus-minus>273.1) were higher than that (203.1<plus-minus>160.5IU/1) of saliva in 7 periodontal patie

研究中使用了Beetrode ^R和锑电极。随着微积分指数0、1、2的增加，包内pH值略有变化，但不显著（r=0.21）。而当微积分指数为3时，pH值下降。4名健康受试者口袋深度与口袋pH值无显著相关。1、2、3 mm袋深pH值范围为ph5.8 ~ ph7.8。4mm的袋深范围pH为6.5 ~ 7.4。而在5 /龋的情况下，牙袋深度与牙袋pH呈线性正相关（r=0.54）。患者牙周袋内pH值较健康人偏碱性。分析患者唾液和GCF中脊髓灰质炎病毒的含量。GCF中的多聚氰胺含量明显高于唾液。据报道，在纯唾液中没有检测到小儿麻痹症。因此，本研究中检测到的全唾液中的多氯胺一定是从龈沟泄漏的。此外，在口袋中观察到的多氯胺的数量与pH呈正相关。7例牙周患者GCF中ALP活性（533.2<正负>273.1）高于唾液中ALP活性（203.1<正负>160.5IU/1）