Enzyme-like FLP Catalysis within Coordination Cages

该项目旨在通过水溶性配位笼实现受挫Lewis对(Flp)的封装。这将提供第一个配位笼结合FLP催化剂的例子，推动酶模拟催化领域的发展。该项目的成功实施将克服FLP催化不能在水溶液中进行的问题，同时借助配位笼提高FLP催化的反应活性和前所未有的选择性。这也将为笼形催化和FLP催化在其他基础有机反应中的应用开辟新的途径。

The project aims to achieve the encapsulation of frustrated Lewis pairs (FLPs) by water-soluble coordination cages. This would provide the first example of coordination cages incorporating FLP catalysts, advancing the field of enzyme-mimic catalysis. The successful execution of this project will overcome the problem that FLP catalysis cannot proceed in aqueous solution, and at the same time bring about improved reactivity and unprecedented selectivity for FLP catalysis with the aid of coordination cages. This will also open new avenues to apply cage catalysis and FLP catalysis to other fundamental organic reactions.