THE EFFECTS OF LOW POWER LASER ON PAIN PROJECTION MECHANISMS

本课题由3项研究组成，旨在阐明其镇痛作用的机制。1)对人红细胞低渗溶血的影响; 2）对钠、钾通道的影响; 3）对DPPc膜（人工膜）的影响。[结果1]激光能稳定受损红细胞膜，激活红细胞的变形能力。[结果2]激光照射后，钾离子浓度增加，钠离子浓度无明显变化。[结果3]激光辐照对相变温度也没有影响。[结论]低功率He-Ne激光照射对DPPC人工膜的物理性能无影响。但对人红细胞的低渗溶血有抑制作用。这表明激光对红细胞膜具有保护作用，使其免于低渗溶血，并使膜稳定。

This project was constructed of 3 studies for clarifing the mechanism of analgesic effect. 1) the effect on hypotonic hemolysis of human red blood cell, 2) the effects on sodium and potasium channel, 3) the effects on DPPc membrane (artificial membrane),[result 1] The laser stabilized the membrane of damaged red blood cells and the deformability was activated by the laser irradiation.[result 2] We observed the potasium ions increseed, but the sodium ions were no changed by the laser irradiation.[result 3] Phase transition temperature was also unchanged by the laser irradiation.[conclusion] These results suggest that low-power He-Ne laser irradiation do not affect the physical characteristics fo artificial DPPC membranes. But the hypotonic hemolysis in human red cells were inhibited by the laser irradiation. This suggest that the laser has protective effects on red cell membranes from hypotonic hemolysis and stabilize the membranes.