A study of effects of fluoride-releasing resin sealants on caries prevntion

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This study was undertaken to investigate the fluoride releasing behavior of experimental resin sealants, fluoride uptake directly under the sealant as well as in the area surrounding the sealants after application of the fluoride releasing sealants to the bovine enamel.1. The rate of fluoride release from samples that were shaken was three times that of control values for one day and 1.8 times that after one day without shaking.There was significant difference in the amount or rate of fluoride release among samples stored in deionized water, phosphate buffer solution or artificial saliva.2. The water sorption of matrix resin and the rate of fluoride release were correlated and the amount of fluoride release progressively increased with increases in water sorption. The order of decrease was DPHA*, DPHA/3G,2.6E/HEMA,2.6E/3G,HD.3. Matrix resins with excellent solubility of PMF were No.10, which consisted of A liquid : DPHA* and B liquid : EMA/1G (75 : 25) +PMF 40 (30%), and No.12, which consisted of A luquid : DPHA* and B luquid : EMA/1G (75 : 25) +PMF60 (15%).The amount of fluoride released from those resin sealants was greater, ranging from 1.7 to 1.9 times that in the control group.4. The concentration of fluoride ions taken up by the bovine enamel after four weeks in samples coated with the experimental group was higher then that in the control group both directly under the sealant and in the area surrounding the sealant. Also, the depth of fluoride ion taken up by the enamel in the area surrounding the experimental sealant was greater than that in the control group.