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Study of ribosome maturation mechanism by the structural analysis of Rat-U13snoRNA complex

Study of ribosome maturation mechanism by the structural analysis of Rat-U13snoRNA complex
通过Rat-U13snoRNA复合物的结构分析研究核糖体成熟机制
批准号:
20247007
负责人:
TANAKA Isao
金额:
$27.54万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (A)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2011

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中文摘要
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英文摘要
Using the proteins from M.musculus (mRAT) and from S.cerevisiae RAT (yRAT), it has been directly proved that a eucaryotic homolog of E. coli tRNA acetyltransferase TmcA (RAT) has the activity of transferring the acetyl group to the specific site of 18S rRNA. It has also been proved that these proteins have the ATPase activity. As a result of crystallization screening, we found that the crystals of RAT from S.cerevisiae of which C-terminal 123 residues are truncated (deltaC123-yRAT) diffract X-rays to 9 A resolution at BL32XU, SPring-8.
期刊论文(79)
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会议论文
DOI: 10.1074/jbc.m109.068098
发表时间: 2010-02-12
期刊: JOURNAL OF BIOLOGICAL CHEMISTRY
影响因子: 4.8
作者: [Naganuma, Takao, Nomura, Naoko, Tanaka, Isao]
通讯作者: Tanaka, Isao
Pyrococcus horikoshii由来アラニルtRNA合成酵素の結晶構造
堀越火球菌丙氨酰-tRNA 合成酶的晶体结构
DOI: --
发表时间: 2009
期刊:
影响因子: --
作者: [Kanang Chaturaphatranon, Mai Sakai, Kazunobu Kogi, Shiro Kohshima, 徳永啓太,曽我部正彰,尾瀬農之,中村彰良,濡木理,姚閔,田中勲]
通讯作者: 徳永啓太,曽我部正彰,尾瀬農之,中村彰良,濡木理,姚閔,田中勲
リボソームの翻訳因子作用中心に位置する動的タンパク質複合体
位于核糖体翻译因子作用中心的动态蛋白质复合物
DOI: --
发表时间: 2010
期刊:
影响因子: --
作者: [Kanno, E., Ishibashi, K., Kobayashi, H., Matsui, T., Ohbayashi, N. & Fukuda, M., 内海利男]
通讯作者: 内海利男
Structural basis for translation factor recruitment to the eukaryotic/archaeal ribosomes, Taiwan-Japan Joint Seminar on Crystallography and IPR Seminar
真核/古菌核糖体翻译因子招募的结构基础,台日结晶学联合研讨会暨知识产权研讨会
DOI: --
发表时间: 2009
期刊:
影响因子: --
作者: [Hori Y, Kobayashi T, Kikko Y, Kontani K, Katada T, Min Yao]
通讯作者: Min Yao
51
    Growth and domain suppression effects on ion conductivity of bulk crystals of lithium ion conducting oxides
    • 批准号:
      16K05930
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $3.16万
    • 财政年份:
      2016
    • 负责人:
      TANAKA Isao
    • 依托单位:
    Creation of electroactive function in single crystals of calcium aluminate electrides by element doping
    • 批准号:
      25420708
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $3.33万
    • 财政年份:
      2013
    • 负责人:
      TANAKA Isao
    • 依托单位:
    Development of the gel coating technique for the automation of the inhibitor search by the X-ray crystal structure analysis
    • 批准号:
      25650015
    • 项目类别:
      Grant-in-Aid for Challenging Exploratory Research
    • 资助金额:
      $2.58万
    • 财政年份:
      2013
    • 负责人:
      TANAKA Isao
    • 依托单位:
    First principles investigation of high ionic conductivity in ionic crystals
    • 批准号:
      24656370
    • 项目类别:
      Grant-in-Aid for Challenging Exploratory Research
    • 资助金额:
      $2.58万
    • 财政年份:
      2012
    • 负责人:
      TANAKA Isao
    • 依托单位:
    海外基金