Glucose- and temperature- dependent regulation of spontaneous firing in SNr GABAergic neurons

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It has not been identified that regulatory mechanisms of persistent high frequency spontaneous firing in SNr GABAergic neuron. Glucose- and temperature- dependent regulation of spontaneous firing in acutely dissociated SNr GABAergic neuron was investigated. Glucose- and temperature- dependent regulation of spontaneous firing in acutely dissociated GABAergic neuron was distinct from the results of the extracellular recording in acute brain slices (Yuan, H. et al, Neurosci Lett 2004). These results suggest that the spontaneous firing in SNr GABAergic neuron could be regulated by the environment around a neuron in brain.