Brain imaging studies on cognitive distortions and cognitive behavioral therapy in patients with eating disorders

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We investigated the functional abnormalities in brain systems during processing of negative stimuli concerning body images in patients with eating disorders. Brain responses were measured using functional magnetic resonance imaging in female patients with eating disorders and healthy young women. Our study showed that distorted cognition of negative stimuli concerning body image in patients with eating disorders were related to enhanced activation in the amygdala and the prefrontal cortex. These abnormal brain functions may help provide better accounts of the psychopathological mechanisms underlying eating disorders.