Functional Analysis of Angptl4 in activation of lipoprotein lipase by insulin
Functional Analysis of Angptl4 in activation of lipoprotein lipase by insulin
批准号:
21890198
负责人:
ADACHI Hironori
金额:
$1.66万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Research Activity Start-up
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2010
中文摘要
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英文摘要
Inactivation of Angptl4 reduced serum TG levels, and this was achieved by activation of LPL by insulin stimulation. STZ treatment or LDL-R KO in Angptl4 KO displayed significant reduction of TG levels upon lipid loading test.
期刊论文(1)
专著(0)
科研奖励(0)
会议论文
Angpt14 dificiency decreases serum triglyceride levels in low-density lipoprotein receptor knockout mice and streptozotocin-induced diabetic mice.
Angpt14 缺乏会降低低密度脂蛋白受体敲除小鼠和链脲佐菌素诱导的糖尿病小鼠的血清甘油三酯水平。
DOI:
--
发表时间:
2011
期刊:
Biochem Biophys Res Commun. [Epub ahead of print]
影响因子:
--
作者:
[Adachi H, Kondo T, Koh GY, Nagy A, Oike Y, Araki E.]
通讯作者:
Araki E.
海外基金