Investigation of the transmission mechanism of RSV among Vietnamese children

越南儿童RSV传播机制调查

• 批准号: 22890137
• 负责人: SUZUKI Motoi
• 金额: $ 2.01万
• 依托单位: Nagasaki University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Research Activity Start-up
• 财政年份: 2010
• 资助国家: 日本
• 起止时间: 2010 至 2011
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-22890137/
• 关键词: RSウイルス; ベトナム; 国際情報交換; RSV感染症; 細気管支炎; 感染症疫学

We investigated the effect of respiratory viruses single and multiple infections on risk of lower respiratory tract infections (LRTIs) in Vietnam. Nasopharyngeal samples were collected from 1,992 hospitalized children with acute respiratory infections and tested for 13 respiratory viruses. 60.9% were positive for at least one virus, and 9.5% had multiple-viral infections. RSV and human metapneumovirus (HMPV) infections independently increased the risk of LRIs. RSV further increased the risk, when co-infected with HRVand HMPV.

我们调查了越南呼吸道病毒单一感染和多重感染对下呼吸道感染(LRTI)风险的影响。1,992名急性呼吸道感染住院儿童的鼻咽样本被采集，并检测了13种呼吸道病毒。60.9%的人至少有一种病毒阳性，9.5%的人有多病毒感染。RSV和人类偏肺病毒(HMPV)感染独立增加了LRIS的风险。当RSV与HRV和HMPV混合感染时，风险进一步增加。

项目成果

Respiratory syncytial virus, its co-infection and paediatric lower respiratory infections

呼吸道合胞病毒及其合并感染与小儿下呼吸道感染

• 发表时间: 2013
• 期刊: Eur Respir J
• 影响因子: 24.3
• 作者: Yoshida LM;Suzuki M;Nguyen HA;Le MN;Vu TD;Yoshino H;Schmidt WP;Nguyen TT;Tho Le H;Morimoto K;Moriuchi H;Dang DA;Ariyoshi K
• 通讯作者: Ariyoshi K

Incidence of Radiologically Confirmed Pneumonia and Haemophilus influenzae type b Carriage before Hib Vaccine Introduction in Central Vietnam

越南中部接种 Hib 疫苗前放射学确诊的肺炎和 b 型流感嗜血杆菌携带情况的发生率

• 期刊: Journal of Infection
• 影响因子: 28.2
• 作者: Lay-Myint Yoshida;Hien-Anh Nguyen;Kiwao Watanabe;Minh Nhat Le;Ai Thi Thuy Nguyen;Huong Thi Thu Vu;Hiroshi Yoshino;Motoi Suzuki;Kensuke Takahashi;Tho Huu Le;Paul E. Kilgore;Karen Edmond;Kim Mulholland;Duc-Anh Dang;Koya Ariyoshi
• 通讯作者: Koya Ariyoshi

Does Respiratory Virus Coinfection Increases the Clinical Severity of Acute Respiratory Infection Among Children Infected With Respiratory Syncytial Virus?

• DOI: 10.1097/inf.0b013e31828ba08c
• 发表时间: 2013-05-01
• 期刊: PEDIATRIC INFECTIOUS DISEASE JOURNAL
• 影响因子: 3.6
• 作者: Harada, Yoshitaka;Kinoshita, Fumiko;Ariyoshi, Koya
• 通讯作者: Ariyoshi, Koya