Understanding the molecular mechanism required for an anchorage-independent growth of CD133-positive ovarian cancer cells
Understanding the molecular mechanism required for an anchorage-independent growth of CD133-positive ovarian cancer cells
批准号:
23800055
负责人:
ARAKI Marito
金额:
$2.08万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Research Activity Start-up
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2012
中文摘要
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英文摘要
Solid tumors are comprised of heterogeneous cells, which seem to play crucial roles in the establishment of drug-resistance and the recurrence of tumor. In this study, we identified genes highly expressed in CD133-positive ovarian cancer cells, named themHEG(Highly-expressed genes in CD133-positive cells), and showed that HEG1-3 play an important role for the anchorage-independent cell growth. Further studies would reveal more precise molecular mechanisms of the anchorage-independent cell growth in CD133-positive ovarian cancer cells.
期刊论文(7)
专著(0)
科研奖励(0)
会议论文
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急性早幼粒细胞白血病治疗药物的筛选方法
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[]
通讯作者:
The Sirtuin inhibitor induces APL cell differentiation
Sirtuin 抑制剂诱导 APL 细胞分化
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Sunami Y, Araki M,Morishita S,Hironaka Y,Edahiro Y,Ohsaka A,Komatsu N]
通讯作者:
Araki M,Morishita S,Hironaka Y,Edahiro Y,Ohsaka A,Komatsu N
The SirT1 Inhibitor Tenovin-6 Induces Monocytic Differentiation in APL Cells
SirT1 抑制剂 Tenovin-6 诱导 APL 细胞单核细胞分化
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[角南義孝、荒木真理人, 他]
通讯作者:
他
海外基金