Development of a micromanipulator tracking brain micromotion in 3D for ultrastable intracellular recording.
Development of a micromanipulator tracking brain micromotion in 3D for ultrastable intracellular recording.
批准号:
23860071
负责人:
OTA Keisuke
金额:
$2.08万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Research Activity Start-up
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2012
中文摘要
动物的大脑在体内会摇晃。另一方面,在实验中细胞内记录电极被固定在基座上。细胞内记录对于阐明大脑中的信息处理是必要的,但是目前的细胞内记录系统在行为动物中没有实现长期稳定的记录。为了解决这个问题,我将开发一个显微操作器,在3D中跟踪大脑的微运动,并旨在同时记录行为动物的两个神经元的膜电位。
英文摘要
Animal brains swags in vivo. On the other hand, the intracellular recording electrode is fastened on to a base in the experiment. The intracellular recording is necessary for elucidating the information processing in the brain, but the current intracellular recording system does not realize a long-term stable recording in behaving animals. To solve this problem, I will develop a micromanipulator tracking brain micromotion in 3D and aim to simultaneously record the membrane potentials from two neurons in behaving animals.
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