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Development of a micromanipulator tracking brain micromotion in 3D for ultrastable intracellular recording.

Development of a micromanipulator tracking brain micromotion in 3D for ultrastable intracellular recording.
开发微操纵器,以 3D 方式跟踪大脑微运动,以实现超稳定的细胞内记录。
批准号:
23860071
负责人:
OTA Keisuke
金额:
$2.08万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Research Activity Start-up
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2012

项目摘要

项目成果

相关文献

中文摘要
翻译
动物的大脑在体内晃动。另一方面,在实验中,细胞内记录电极被固定在一个基座上。细胞内记录是阐明大脑信息处理过程所必需的,但目前的细胞内记录系统还不能在行为动物中实现长期稳定的记录。为了解决这个问题,我将开发一种3D跟踪大脑微运动的微操作器,目的是同时记录行为动物的两个神经元的膜电位。
英文摘要
Animal brains swags in vivo. On the other hand, the intracellular recording electrode is fastened on to a base in the experiment. The intracellular recording is necessary for elucidating the information processing in the brain, but the current intracellular recording system does not realize a long-term stable recording in behaving animals. To solve this problem, I will develop a micromanipulator tracking brain micromotion in 3D and aim to simultaneously record the membrane potentials from two neurons in behaving animals.
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