Elucidation of molecular mechanism for maintaining chromosome alignment regulated by novel protein, CAMP

准确的染色体分离需要在中期赤道区进行正确的染色体排列。最近，我们鉴定了在维持染色体比对中起重要作用的新型分子CAMP（EMBO J，2011）。在这项研究中，我们研究了维持染色体排列的分子机制介导的CAMP。因此，我在有丝分裂期间鉴定了CAMP相互作用蛋白，然后评估了CAMP和参与染色体排列的相互作用蛋白之间的关系。

Accurate chromosome segregation requires proper chromosome alignment at equatorial region in metaphase. Recently, we identified novel molecule, CAMP, which plays an important role in a maintaining of chromosome alignment (EMBO J, 2011). In this study, we examined a molecular mechanism for the maintaining of chromosome alignment mediated by CAMP. Therefore, I identified a CAMP interacting protein during mitosis and then assessed a relationship between CAMP and the interacting protein involved in maintainingof chromosome alignment.