Development of p53 expressing viral vector using human insulator.
Development of p53 expressing viral vector using human insulator.
批准号:
23890046
负责人:
MORI Mayuyo
金额:
$2.08万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Research Activity Start-up
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2012
中文摘要
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英文摘要
Efficient and continuous expression of a therapeutic transgene is a key factor for improving the efficacy of gene therapy. Some insulators are known to contribute to continuous high-level expression of a therapeutic transgene. In this study, we modified an adeno-associated virus serotype 2 (AAV2) vector expressing p53 from the mouse muscle creatine kinase gene promoter-enhancer (Ckm).
期刊论文(2)
专著(0)
科研奖励(0)
会议论文
アプレピタントは婦人科腫瘍における化学療法の悪心嘔吐軽減に有効である
阿瑞吡坦可有效减少妇科肿瘤化疗引起的恶心和呕吐。
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Kazue Mizuno, Hiroshi Fujisawa, Horacio Cabral, Nobuhiro Nishiyama and Kazunori Kataoka, 柴田 彩, 内野繭代]
通讯作者:
内野繭代
An adeno-associated virus vector efficiently and specifically transduces mouse skeletal muscle
腺相关病毒载体可高效、特异地转导小鼠骨骼肌
DOI:
--
发表时间:
2011
期刊:
Mol Miotechnol
影响因子:
--
作者:
[Murakami I, Fujii T]
通讯作者:
Fujii T
海外基金