Assessment of myocardial ischemia using 3D contrast speckle tracking echocardiography

三维(3D)散斑跟踪成像使我们能够在相同的节拍中评估周向、纵向和径向应变。然而，三维斑点跟踪超声心动图的低帧频和低图像质量是量化左心功能的潜在限制。超声心动图造影剂提高了心内膜的清晰度，可以准确地量化左室容量和评估室壁运动异常。在动物实验中，我们发现3D斑点跟踪超声心动图比2D斑点跟踪超声心动图更能重复性地进行应变分析。

Three-dimensional (3D) speckle tracking imaging allows us to assess circumferential, longitudinal and radial strains in the same beat. However, low frame rates and low image quality of 3D speckle tracking echocardiography are potential limitation to quantify the left ventricular (LV) function. Echocardiographic contrast agents improve endocardial definition, allowing the accurate quantification of LV volumes and the assessment of wall motion abnormalities. From animal experiment, we found that 3D speckle tracking echocardiography with contrast (30 ml/min intravenous infusion, mechanical index -14 dB) was the more reproducible technique for the strain analysis than 2D speckle tracking echocardiography.