Effect of fetal exposure to DEHP on nutrition status, hippocampus and hypothalamus in offspring

在胎儿期暴露于邻苯二甲酸二（2-乙基己基）酯（DEHP）会降低新生小鼠的葡萄糖浓度，并导致营养不良。此外，我们检查了DEHP对大脑的影响，因为葡萄糖是重要的营养来源。DEHP暴露改变了记忆中涉及的因素。此外，高脂饮食还改变了更多的因素，这可能表明饮食环境对记忆的影响。综上所述，胎儿暴露于DEHP可能会导致后代营养不良，并在成熟阶段对大脑产生影响。我们必须进行进一步的研究，以澄清这些机制。

Exposure to di(2-ethylhexyl)phthalate (DEHP) during fetal periods decreased glucose concentration in neonatal mice, and lead to malnutrition. In addition, we examined the effect of DEHP on the brain, because glucose is significant source of nutrient. DEHP exposure changed the factors involved in memory. Furthermore, high fat diet also changed more factors, which may indicate that dietary environment effect on memory. Taken together, fetal exposure to DEHP may induce malnutrition in offspring, and effect on the brain during mature stage. We must carry out further research to clarify these mechanisms.