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Prototype development of portable and high-efficiency imaging device in nuclear medicine

核医学便携式高效成像设备原型开发

基本信息

批准号：
11470196
负责人：
HORIGUCHI Takayoshi
金额：
$ 9.47万
依托单位：
HIROSHIMA INTERNATIONAL UNIVERSITY
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (B)
财政年份：
1999
资助国家：
日本
起止时间：
1999 至 2001
项目状态：
已结题

项目摘要

The purpose of present study is to develop a prototype of portable and high-efficiency imaging device in nuclear medicine. In 1999 fiscal year, a 12-channel CdZnTe detector array (each 4.83×4.83 mm, 2 mm thickness) was fabricated in special design, and energy gain of amplifier in each channel was adjusted. This array module was operated in room temperature and fundamental characteristics such as energy resolution was examined by MCA system. In 2000 fiscal year, this array module was scanned in one direction, and energy-selected counts were read into a computer with radioactive point sources and a mini-phantom. A software was developed to construct nuclear medical images from the data. Another high-resolution Si-PIN X-ray detector with thermoelectric cooler was introduced to compare the energy resolution and detection efficiency with those of the array module. In final fiscal year, pulse-motor driven XY-stage was prepared to precisely scan in two dimensional region. A flat radioactive ^<241> Am source of large area (100×100 mm) was prepared in special order. By using this flat source and CdZnTe array module, two-dimensional pseudo-images in nuclear medicine were obtained in several energy bins and compared with one-dimensional pseudo-image with Si-PIN detector. As a result, present array module was found to have much larger efficiency than Si-PIN detector. Moreover, this module has better energy and space resolutions than conventional NaI(T1) scintillator and is very promising in nuclear medical applications.

本研究的目的是研制一种便携式、高效率的核医学成像装置样机。1999年，我们制作了12通道CdZnTe探测器阵列（4.83× 4.83mm，2 mm厚），并对各通道放大器的能量增益进行了调整。该阵列模块在室温下运行，并通过MCA系统检查了基本特性，如能量分辨率。在2000财政年度，这个阵列模块被扫描在一个方向上，能量选择计数被读入一台计算机与放射性点源和一个迷你幻影。开发了一个软件来从数据中构建核医学图像。介绍了另一种采用热电制冷的高分辨率Si-PIN X射线探测器，并与阵列模块的能量分辨率和探测效率进行了比较。在最后一个财政年度，脉冲电机驱动的XY工作台准备在二维区域精确扫描。研制<241>了大面积（100×100 mm）的平面~（40）Am放射性源。利用该平面光源和CdZnTe阵列模块，在多个能量仓中获得了核医学中的二维伪像，并与Si-PIN探测器的一维伪像进行了比较。结果发现，本阵列模块具有比Si-PIN探测器大得多的效率。此外，该组件具有更好的能量和空间分辨率比传统的NaI（T1）闪烁体，是非常有前途的核医学应用。