Development of chemosensors based on molecular spin-crossover metal complexes

基于分子自旋交叉金属配合物的化学传感器的开发

• 批准号: 459356612
• 负责人: Privatdozent Dr. Marat Khusniyarov
• 金额: --
• 依托单位: Lehrstuhl für Anorganische und Allgemeine Chemie
• 依托单位国家: 德国
• 项目类别: Research Grants
• 资助国家: 德国
• 项目状态: 未结题
• 来源: https://gepris.dfg.de/gepris/projekt/459356612?language=en
• 关键词: Development; chemosensors; based; molecular; spin

In this project, unique phosphates and fluoride responsive chemosensors will be developed. Special receptor groups will be introduced into molecular spin-crossover iron(II) complexes to allow chemical control of the spin state in solution at room temperature. The change of the spin state in the presence of anions will lead to the desired colorimetric and magnetic response. The functionality, sensitivity, and selectivity of chemosensors will be evaluated. The potential of these systems to act as switchable (intelligent) MRI contrast agents will be examined.

在这个项目中，将开发独特的磷酸盐和氟化物反应性化学传感器。特殊的受体组将被引入分子自旋 - 横断铁（II）复合物中，以允许在室温下溶液中的旋转状态进行化学控制。在阴离子存在下旋转状态的变化将导致所需的比色和磁反应。将评估化学传感器的功能，灵敏度和选择性。将检查这些系统充当可切换（智能）MRI对比剂的潜力。