The method of estimation of stress in child abuse/neglect
The method of estimation of stress in child abuse/neglect
批准号:
11557034
负责人:
TANEGASHIMA Akio
金额:
$2.3万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B).
财政年份:
1999
资助国家:
日本
项目状态:
已结题
起止时间:
1999 至 2000
中文摘要
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英文摘要
It is difficult to evaluate the extent of stress in cases of suspected child abuse/neglect in a medico-legal autopsy. To elucidate the influence upon thymocytes differentiation, we investigated that the morphological change of the thymus and the proportion of the thymocyte subpopulation in abused/neglected children. We found that the relative number of CD4+CD8+ double positive (DP) thymocytes decreased in the abused/neglected children. It was presumed that the selective decrease in the number of the immature DP thymocytes with CD3 ^<- to low> bcl-2^<low> caused the thymic involution in the abused/neglected children. It is proposed that the alteration in the proportion of thymocyte subpopulations could be an index for the degree of the stress in cases of child abuse/neglect.
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Tanegashima A. et al.: "Intrathymic lymph nodes in humans."Journal of Anatany. 198(in press). (2001)
Tanegashima A. 等人:“人类胸腺内淋巴结。”Anatany 杂志。
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Tanegashima A.et al.: "Tissue-specific expression of LeY antigen in high endothelial venules of human lymphoid tissues."Glycoconjugate Journal. 16. 809-819 (1999)
Tanegashima A.et al.:“LeY 抗原在人淋巴组织的高内皮小静脉中的组织特异性表达。”Glycoconjugate Journal。
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Tanegashima A.et al.: "Human parathymic lymph node : morphological and functional significance."Immunology. 97. 301-308 (1999)
Tanegashima A.et al.:“人类副胸腺淋巴结:形态学和功能意义。”免疫学。
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Tanegashima A et al.: "Estimation of stress in child neglect from thymic involution."Forensic Science International. 101. 55-63 (1999)
Tanegashima A 等人:“胸腺退化对儿童忽视造成的压力的估计。”国际法医科学。
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Tanegashima A, et al.: "Tissue-specific expression of Le^Y antigen in high endothelial venules of human lymphoid tissues."Glycoconjugate Journal. 16. 809-819 (1999)
Tanegashima A 等人:“Le^Y 抗原在人淋巴组织的高内皮小静脉中的组织特异性表达。”Glycoconjugate Journal。
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