权益分类	功能权益	普通用户	{{item.name}}会员
{{category.name}}	{{benefitItem.name}}

Oral Microbial Flora in Institutionalized Elderly People

机构老年人的口腔微生物菌群

基本信息

批准号：
12470427
负责人：
MORITA Mitsuhiko
金额：
$ 6.21万
依托单位：
TSURUMI UNIVERSITY
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (B)
财政年份：
2000
资助国家：
日本
起止时间：
2000 至 2001
项目状态：
已结题

项目摘要

The studies aimed not only to determine the explication for the mechanism causing oral disease and to obtain the basic data for oral health care, but to reveal the relationship between the method of oral cleaning, oral disease, dysphagia and infectious disease. Opportunistic pathogens such as Candida, staphylococci and MRSA, pathogenic causing dental caries such as mutans streptococci and lactobacilli, pathogenic causing periodontitis, relationship between oral microbial flora and quantity of saliva, buffer capacity, biochemical behavior of saliva, design and material of denture, and number of teeth were investigated.Within the limits of this study, the following conclusions were drawn :1. Owing to reduction of general condition and ADL, a tendency of increase in the number of Candida in the oral cavity was recognized.2. Positive correlation between the number of Candida and lactobacilli was confirmed.3. After FBS control, the salivary buffering capacity and the number of lactobacilli and mutans streptococci in saliva were significantly improved from the pre-FBS control in diabetes mellitus patients.4. After the instruction for oral cleaning to institutionalized elderly, increase in the quantity of saliva, improvement on the salivary buffering capacity, reduction of the number of microbial colonization and decrease of the mean amount of CH_3SH were recognized.5. The use of a tongue brush was beneficial for the improvement of oral hygiene on the dependent elderly.

本研究的目的不仅在于阐明口腔疾病的发病机制，为口腔保健提供基础资料，而且在于揭示口腔清洁方法与口腔疾病、吞咽困难和感染性疾病之间的关系。通过对念珠菌、葡萄球菌、MRSA等口腔致病菌，变形链球菌、乳酸杆菌等龋齿致病菌，牙周炎致病菌，口腔微生物植物群与唾液量、缓冲能力、唾液生化行为、义齿设计、材料、牙数等的关系的研究，得出以下结论：1.结论：1.随着患者一般情况和日常生活能力的下降，口腔念珠菌数量有增加的趋势.假丝酵母菌数与乳酸杆菌数呈正相关. FBS控制后，糖尿病患者唾液缓冲能力、唾液中乳酸杆菌和变形链球菌数量较FBS控制前显著提高.对机构老人进行口腔清洁指导后，唾液量增加，唾液缓冲能力提高，微生物定植数量减少，CH_3SH平均含量降低.使用舌刷有利于改善老年人的口腔卫生状况。