A longitudinal study on correlation between weight cycling and changes of risk factors for lifestyle-related disease of middle and advance ages

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The purpose of this study is to elucidate the correlation between weight cycling and changes of risk factors for lifestyle-related diseases.The subjects are middle aged and advanced aged who have consulted health medical examination in the city of A for several years in succession. We divided them into three groups (obesity group, moderate group and lean group) by their body fat %, and we observed their fluctuation of body fat % for several years and divided them into three subgroups (decreasing group, unchangeable group and increasing group).We compared the fluctuation with three subgroups in each groups.The results were as follows. In males, decreasing subgroup of moderate group had a statistically significant decrease in SBP, DBP, TC, LDL-C, RBC, Hb, Ht. Unchangeable subgroup had a significant increase in Hb. Other subgroups had no significant changes. In lean group of females decreasing subgroup had a significant decrease in Tc, LDL-C and TG. Moderate subgroup had a significant increase in r-GPT, Hb and Ht. In obesity group decreasing subgroup had a significant increase in HbAlc.