C-type lectins and innate immunity in barramundi

该项目旨在确定天然免疫的关键成分甘露聚糖结合凝集素(MBL)，并建立MBL的定量分析方法。该项目进一步旨在研究MBL在引起Barramundi和人类疾病的新链球菌感染过程中的作用。定量测定将与更传统的测定相结合，以评估添加饲料对巴拉蒙迪天然免疫系统的影响，以及它们在应激时期的抗病能力。这个项目将增加我们对这种鱼的先天免疫途径的了解，并帮助开发改进的饲养策略。

The project aims to identify mannan binding lectins (MBL), key components of innate immunity, in barramundi and to develop quantitative assays for MBL. The project further aims to investigate the role of MBL in infectious processes of Streptococcus iniae, which causes disease in barramundi and humans. Quantitative assays will be used in conjunction with more traditional assays to evaluate the effect of supplemented feeds on the innate immune system of barramundi and their disease resistance during times of stress. This project will increase our understanding of innate immune pathways in this fish species and aid development of improved feeding strategies.