C-type lectins and innate immunity in barramundi

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The project aims to identify mannan binding lectins (MBL), key components of innate immunity, in barramundi and to develop quantitative assays for MBL. The project further aims to investigate the role of MBL in infectious processes of Streptococcus iniae, which causes disease in barramundi and humans. Quantitative assays will be used in conjunction with more traditional assays to evaluate the effect of supplemented feeds on the innate immune system of barramundi and their disease resistance during times of stress. This project will increase our understanding of innate immune pathways in this fish species and aid development of improved feeding strategies.