Realizing Human Brain Stimulation of Deep Regions Based on Novel Personalized Electrical Computational Modelling

基于开发用于局灶性和深部脑刺激的个性化计算物理模型的目的，我们使用数值和实验技术相结合的方法研究了刺激剂量特性。实验表明，集中刺激集中在大脑小区域的单个手指的可能性，以高分辨率展示焦点。此外，双半球经颅刺激应用的新见解，提出了深皮层刺激下肢。最后，与个性化脑刺激模拟器集成的微物理神经元模型的开发取得了进展，以研究干扰现象。

Based on the aim of developing a personalized computational physical model for focal and deep brain stimulation, we investigated stimulation dose characteristics using a combined approach of numerical and experimental techniques. The experiments showed the possibility of focal stimulation of individual hand fingers that are condensed in a small area of the brain demonstrating focality with high resolution. In addition, new insight into the dual-hemisphere transcranial stimulation application was presented for deep cortical stimulation of the lower limb. Finally, progress in the development of a micro-physical neuron model integrated with the personalized brain stimulation simulator was achieved to investigate interferential phenomena.