The establishment of the functional bowel disorders treatment based on the pathophysiological study

对正常对照组4例，慢性便秘组3例进行乙状结肠和直肠压力活动测定。我们使用了一个包含三个应变压力传感器的柔性探头（P31-30: KONIGSBERG INSTRUMENTS）。分别位于离肛门2、12和27厘米处。探针连接在便携式口袋监视器（gms -300: STAR MEDICAL.）上。INC.)和压力活动记录。分析了每小时收缩波的数量，并将收缩波分为码型I-IV型。与慢性便秘患者相比，正常组的波数较多，且餐后2 ~ 4小时波数增加。此外，慢性便秘患者的压力活动比正常患者少。它不承认餐后2 ~ 4小时的波数增加，也不承认餐后1 ~ 4小时的波数增加。它认为在正常情况下，它变得更加加速，并伴随着膳食的主动收缩波。在慢性便秘中，胃结肠反射是由膳食引起的，这是错误的。但进一步病例的积累似乎是必要的，因为目前病例数量很少。采用便携式袖珍监护仪从肛门处测量乙状结肠和直肠压力约7小时，可记录患者在良好的生活质量和较自然的状态下的负荷情况。认为这种方法对功能性肠病的病理生理检查具有重要意义。在未来，如果增加24小时的测量，对传播压力波的详细分析，结合其他结直肠检查的回顾，直肠活检的回顾，认为有可能开发更准确的治疗功能性肠病。少

We measured the pressure activity of sigmoid colon and rectum to the normal control 4 cases, the chronic constipation 3 cases. We used a flexible probe containing three straingauge pressure transducers (P31-30 : KONIGSBERG INSTRUMENTS. INC.) that were located 2,12 and 27cm from the anus. The probe was attached to a portable pocket monitor (GMMS-300 : STAR MEDICAL.. INC.) and pressure activity recorded.The number of the contraction waves for every one hour was analyzed, and moreover we classified the contraction waves into I-IV type waves of Code.In the normal cases there were many numbers of the waves compared with the chronic constipation patients and the number of the waves in 2-4 hours after meal increased. Moreover, it admitted the increase number of the wave of the I, II, IV.type.Chronic constipation patients showed less pressure activity than the normal cases. It didn't admit the increase of the number of the waves of 2-4 hours after meal and it admitted the increase of neither t … More he I-IV type waves.It thought that it became more accelerate which is accompanied by the active contraction wave by the meal in the normal cases. In the chronic constipation, the fact that a gastrocolic-reflex by the meal is done in the fault was suggested.But the accumulation of further case seems to be necessary, because there are currently few numbers of the cases.The way of measuring pressure in the sigmoid colon and rectum for about 7 hours from the anus using the portable pocket monitor, could record the load of the patient in the good quality of life, and the more natural condition.It thought that this way was important as the way of examining the pathophysiological of the functional bowel disorder.In the future, if adding 24hr measurements, the detailed analysis of the propagating pressure waves, the reviewing which combines the other colorectal examination, the reviewing of a rectum biopsy, it thought that it is possible development of the more accurate treatment of the functional bowel disorder. Less