Influences of stellate ganglion block and near-infrared irradiation around stellate ganglion on the activity of brain cell
Influences of stellate ganglion block and near-infrared irradiation around stellate ganglion on the activity of brain cell
批准号:
14571903
负责人:
YOKOYAMA Kozo
金额:
$1.79万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2002
资助国家:
日本
项目状态:
已结题
起止时间:
2002 至 2003
中文摘要
本研究观察星状神经节阻滞(SGB)或星状神经节周围线性近红外线照射(SGR)对治疗后30 mm额叶皮层脑细胞活动的影响,并对脑电波进行傅立叶变换。然后,我们试图检查治疗后脑电波的90%频谱边缘频率(SEF 90)、频谱中值频率(SMF)和相对功率的变化。SGG后15 min,非阻断侧SEF 90值和SMF值逐渐升高,阻断侧SEF 90值在20 ~ 30 mm范围内逐渐升高,SGR组在90 J/cm ~ 2范围内逐渐升高结果表明,SGB和180 J/cm 2 SGR组的脑细胞均具有激活作用,其中90 J/cm 2 SGR组的θ波相对功率较SGB组明显增加,360 J/cm 2 SGR组的脑细胞相对功率、SEF 90值和SMF值均较SGB组明显增加,而180 J/cm 2 SGR组的脑细胞相对功率、SEF 90值和SMF值均较SGB组明显增加,提示SGB和180 J/cm 2 SGR组的脑细胞相对功率、SEF 90值和SMF值均较SGB组明显增加,提示SGB和180 J/cm 2 SGR组的脑细胞相对功率、SEF 90值和SMF值均较SGB组明显增加,而360 J/cm 2 SGR组的脑细胞相对功率、SEF 90值和SMF值均较SGB组明显增加。结果表明,360 J/cm ~ 2 SGR对脑细胞活性有镇静作用,90-180 J/cm ~ 2 SGR对脑细胞活性有刺激作用,90 - 180 J/cm ~ 2 SGR对脑细胞活性有镇静作用,对脑细胞活性无刺激作用,90-180 J/cm ~ 2 SGR对脑细胞活性无刺激作用,90 - 180 J/cm ~ 2 SGR对脑细胞活性无刺激作用,90-180 J/cm ~ 2 SGR对脑细胞活性无刺激作用。2SGR将用于治疗近远期脑激活,此外,360 J/cm^2 SGR有可能抑制脑细胞的过度兴奋,从而使其正常化。
英文摘要
In this study, it was investigated whether stellate ganglion block(SGB)or several doses of linearly near-infrared irradiation around stellate ganglion(SGR)had some influences on brain cell activity in frontal cortex 30 mm after treatment.Brain waves were measured and performed Fourier transform. Then, we tried to examine changes of 90% spectral edge frequency(SEF90), spectral median frequency(SMF)and relative power of brain waves following treatment.In the SGB, relative power of fast activity, SEF90 values and SMF values were increased 15 min after SGB on the unblocked side and increased between 20 mm and 30 mm by degrees on the blocked side.In the SGR groups between 90 J/cm^2 and 180 J/cm^2, relative power of fast activity, SEF90 values and SMF values increased on bilateral sides.Therefore, it was suggested that both SGB and these doses of SGR activated brain cells.Especially, relative power of theta-wave increased in the dose of 90 J/cm^2 SGR group more than in SGB group.On the other hand, in 360 J/cm^2 SGR group relative power of fast activity, SEF90 values and SMF values were decreased.It was suggested that 360 J/cm^2 SGR had sedative action on brain cell activity as compared with 90-180 J/cm^2 SGR.It was concluded that 90-180 J/cm^2 SGR had the same stimulatory action as SGB.This SGR treatment is non-invasive for patients and 90-180 J/cm^2 SGR will be applied for the treatment of brain activation in the near friture.In addition, there is a possibility that 360 J/cm^2 SGR will suppress hyperexcitability of brain cells and then normalize them.
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