Cranioplasty using an internal absorbable distraction device
Cranioplasty using an internal absorbable distraction device
批准号:
16591798
负责人:
KOMURO Yuzo
金额:
$2.24万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2004
资助国家:
日本
项目状态:
已结题
起止时间:
2004 至 2006
中文摘要
多年来,使用牵引成骨的颅骨成形术一直用于颅缝早闭患者。该技术目前的缺点之一是必须进行第二次手术来移除器械。为了在不进行第二次手术的情况下进行这项技术,我们使用可吸收的牵引装置在兔子身上进行了颅骨牵引,在顶骨区域进行了截骨,并在顶骨区域放置了可吸收的牵引装置。可吸收牵引器械由聚乳酸制成。术后5天开始牵引。牵引宽度为0.5mm/d。继续牵引,直到总宽度达到10 mm。通过X线片评估牵张效果,成功牵张颅骨。聚乳酸是一种用于骨固定植入物的可生物降解材料。内部可吸收牵引装置的主要缺点是与金属部件相比其强度较低。在我们的实验中,已经证明可吸收装置适合于颅骨牵张。
英文摘要
For years, cranoiplasty using distraction osteogenesis has been used for patients with craniosynostosis. One of the current disadvantage of this technique is the necessity of a second operation to remove devices. For the purpose of performing this technique without a second operation, we performed cranial advancement by distraction using an absorbable distraction device in rabbits.Osteotomy was performed in the parietal region and an absorbable distraction device was placed in the parietal region. An absorbable distraction device was manufactured from polylactic acid. Distraction was initiated 5 days postoperatively. The width of distraction was 0.5mm per day. Distraction was continued until the total width was up to 10mm. The effect of distraction was assessed on roentgen-film.Cranial bone was successfully distracted.Polylactic acid is a biodegradable material used for bone fixation implants. The main disadvantage of an internal absorbable distraction device is its lower intensity compared with metallic components. In our experiments, it has been proven that an absorbable device is fit for the distraction of cranial bone.
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