The effects of oral appliance on sleep apnea syndrome and influence of oral appliance on jaw muscle activities

口腔矫治器对睡眠呼吸暂停综合征的影响及口腔矫治器对颌肌活动的影响

• 批准号: 16591950
• 负责人: ABEKURA Hitoshi
• 金额: $ 2.18万
• 依托单位: HIROSHIMA UNIVERSITY
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2004
• 资助国家: 日本
• 起止时间: 2004 至 2005
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-16591950/
• 关键词: SLEEP APNEA SYNDROME; SLEEP SPLINT; MANDIBULAR POSITION; MUSCLE ACTIVITY; MASTICATORY MUSCLE; スリーブスプリント

It is pointed out that there are many potential patients of sleep apnea syndrome. From the result of questionnaire investigation that has been done for the Hiroshima university dental school student, it was suggested that there were many potential patients of this disease without subjective symptom. In other words, social influence of this disease can't be ignored and this is the urgent subject.An oral appliance is considered effective and useful as a countermeasure of dental treatment. There ere few studies about adverse effect caused by long term installation period of appliance. So, we examined the relationship between the amount of forward mandibular movement by wearing the oral appliance and the change of jaw muscle activities under the experimental condition. When we consider the results of the change of activity indexes under the experimental clenching of maximum, minimum, 20% and 40% MVC, it was suggested that the amount of the forward mandibular movement, about 2/3 of the maximum protrusive excursion distances could be acceptable.Furthermore, a focus was put on the amount of oral appliance vertical thickness, and we examined the muscle activities during the actual night sleep. Two types of appliances with vertical dimensions of 3 (S3) and 6 mm (S6) were made for every subject. The minimum splint thickness was decided 3 mm to prevent perforation of the surface of the appliance during use and adjustment and the 6mm thickness was applied clinically as the maximum thickness after considering level of comfort. The effects of oral appliances with two different vertical thickness on nocturnal electromyographic (EMG) activities (the integrated EMG values) were evaluated using a portable EMG recorder. From the analysis of muscle activities during sleep at night, it was suggested that the oral appliances should be as thin as possible considering long term installation period of appliance.

指出有许多潜在的睡眠呼吸暂停综合征患者。从对广岛大学牙科学院学生的问卷调查结果来看，有许多潜在的该病患者没有主观症状。换句话说，这种疾病的社会影响不容忽视，这是迫在眉睫的问题。一种口腔用具被认为是有效和有用的，作为一种对策的牙科治疗。关于器具长时间安装造成的不良影响的研究很少。因此，我们研究了在实验条件下佩戴口腔矫治器时下颌前移量与下颌肌肉活动变化的关系。考虑最大、最小、20%、40% MVC实验握紧下活动指标的变化结果，认为下颌前移量约为最大前突偏移距离的2/3是可以接受的。此外，重点放在口腔用具垂直厚度的量，我们检查肌肉活动在实际夜间睡眠。为每位受试者制作两种垂直尺寸分别为3 （S3）和6 mm （S6）的器具。为了防止矫治器在使用和调整过程中表面穿孔，确定最小夹板厚度为3mm，考虑到舒适度，临床上采用6mm厚度作为最大厚度。采用便携式肌电记录仪评估两种不同垂直厚度口腔器械对夜间肌电活动（综合肌电值）的影响。从夜间睡眠时的肌肉活动分析，建议考虑到口腔矫治器的安装时间较长，矫治器应尽可能薄。