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Development of chemiluminescent probes for the bioscience

Development of chemiluminescent probes for the bioscience
生物科学化学发光探针的开发
批准号:
17510176
负责人:
TERANISHI Katsunori
金额:
$2.3万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2005
资助国家:
日本
项目状态:
已结题
起止时间:
2005 至 2006
关键词:

项目摘要

项目成果

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中文摘要
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英文摘要
A super oxide is one of active oxygens and is concerned with the immune response and the tissue damage which can be put in the living body, and its abundance is kept by "generation and resolution" appropriately in a healthy living body. Analyses of a super oxide of a living body are one of means to know the immunity power and a tissue damage, and via reacting an analyzed chemiluminescence method changes a super oxide th light signal, and is one of the sensitive assays. the luminous compound which issues blue light or a green light (luminous probe) is used by the present chemical emission spectrometry. The quantity of light which reaches light-sensitive cell for light absorption by a pigment falls remarkably, and these luminescent colors are obstruction of measurement. Development of a luminous compound luminous wavelength possesses in the long wavelength region which can excel optical transparency was tried by this research.Chemical bonding react to a super oxide and stick the elements … More who generate the energy into the fluorescent molecule which issues red fluorescence, the organization which flashes from red fluorescent molecule using an energy transfer was used. When chemical synthesis did this luminous molecule, and a luminous Noh play was estimated using the super oxide occurrence system, emission intensity reacted to a super oxide and didn't cause emission of light from the elements who generate the energy, and confirmed the emission of light only of red light, and moreover confirmed the high thing more than the former luminous compound. Since putting it in this emission of light, it was proved that an energy transfer has formed efficiently. A luminous compound which reacts to a super oxide and is different from the elements who generate the energy in the combination style with the red fluorescent molecule, after several kinds of emission intensity of chemical synthesis perilla was estimated, it was revealed that this combination style influencesemission intensity remarkably. Less
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会议论文
Luminescence of Imidazo[1,2-α]pyrazin-3(7H)-one Compounds
咪唑并[1,2-α]吡嗪-3(7H)-酮化合物的发光
DOI: --
发表时间: 2007
期刊: Bioorganic Chemistry 35
影响因子: --
作者: [Shibata J, Ren F, Nishizawa M, Fujno M, Iwatani Y, Matsuda M, Miura H, Tanaka H, Sugiura W., K.Teranishi, K.Teranishi]
通讯作者: K.Teranishi
イミダゾキノキザリノン化学発光物質、その製造法、および発光分析法
咪唑喹喔啉酮化学发光物质、其制造方法以及发光分析方法
DOI: --
发表时间: 2006
期刊:
影响因子: --
作者: []
通讯作者:
シクロデキストリン誘導体の単離精製方法
环糊精衍生物的分离纯化方法
DOI: --
发表时间: 2005
期刊:
影响因子: --
作者: []
通讯作者:
DOI: --
发表时间: 2006
期刊:
影响因子: --
作者: [Tanaka T., et al., 中島芳浩, 中島芳浩, 中島芳浩, 中島芳浩]
通讯作者: 中島芳浩
12
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