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Development for analytic system of real-time voiding manner using the small-type trasnrectal probe

小型经直肠探头实时排尿方式分析系统的研制

基本信息

批准号：
17591695
负责人：
OKIHARA Koji
金额：
$ 2.37万
依托单位：
Kyoto Prefectural University of Medicine
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
2005
资助国家：
日本
起止时间：
2005 至 2006
项目状态：
已结题

项目摘要

We assessed the clinical efficacy of real-time voiding transrectal ultrasound examination with the aim that this novel method can be feasible in evaluating urinary function. This ultrasound system using the specific small-type trasnrectal probe can be navigated the dynamic change of the prostatic urethra as well as the membrounous urethra. First, we analyzed the manner of opening and closing pattern in the prostatic and membrounous urethra in the cases without bladder outlet obstruction. In men without bladder outlet obstruction, bladder neck opened immediately in the early phase of micturition, and the prostatic as well as the membrounous urethra with the diameter measuring from 2 to 3 cm opened continuously until the ending phase of the micturition. The diameter of the urethra was tapered proportionally. There was no significant difference in each section of the diameter as well as of the opening velocity in the urethra which was located apart from 1 cm at the bladder neck. In additi … More on, maximum flow rate in the examination of the uroflowmetry was associated with the opening diameter of the bladder neck. In patients with benign prostatic hyperplasia who were suffering from bladder outlet obstruction, it was difficult to navigate all the section of the urethra, and was impossible to measure the diameter of the urethra on the navigation time between 12 and 16 seconds. The time for dilating the bladder neck was delayed compared to those without bladder outlet obstruction, and the diameters in the each section were opened completely 8 seconds after the navigation. In prostate cancer patients who were underwent radical prostatectomy and had no symptoms for bladder outlet obstruction, the bladder neck opened prior to the micturition, and the lengths for the membrounous urethra were significantly short in cases with urinary incontinence and/or urethral stricture than in those without bladder outlet obstruction. Specifically, in the normal control cases in men with radical prostatectomy, the opening and closing manner in the urethra was quite similar to that in the normal cases without the surgery of radical prostatectomy. Less

我们评估了实时排尿经直肠超声检查的临床效果，目的是这种新的方法可以在评估泌尿功能的可行性。该系统采用特殊的小型经直肠探头，可对前列腺尿道和膜状尿道的动态变化进行导航。首先分析无膀胱出口梗阻的前列腺及膜状尿道的开闭方式。无膀胱出口梗阻者，膀胱颈在排尿早期即开放，前列腺及膜状尿道持续开放，直径2 ~ 3cm，直至排尿末期。尿道的直径成比例地变细。膀胱颈外1cm处尿道各段的直径及张开速度无显著性差异。此外， ...更多信息尿流率检查中最大尿流率与膀胱颈开口直径有关。在患有膀胱出口梗阻的良性前列腺增生患者中，很难导航尿道的所有部分，并且在12至16秒的导航时间内无法测量尿道的直径。膀胱颈扩张时间较无膀胱出口梗阻组延迟，各断面直径在导航后8 s完全开放。前列腺癌根治术后无膀胱出口梗阻症状者，膀胱颈在排尿前开放，有尿失禁和/或尿道狭窄者膜状尿道长度明显短于无膀胱出口梗阻者。特别是，在根治性尿道切除术后的正常对照病例中，尿道的打开和关闭方式与未进行根治性尿道切除术的正常病例非常相似。少

项目成果

期刊论文数量（23）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Overexpression of XIAP expression in renal cell carcinoma predicts a worse prognosis.

DOI：
10.1016/s0022-5347(08)60387-0
发表时间：
2007-04
期刊：
International journal of oncology
影响因子：
5.2
作者：
Y. Mizutani;H. Nakanishi;Yong Nan Li;Hiroki Matsubara;Kosuke Yamamoto;N. Sato;T. Shiraishi;
通讯作者：
Y. Mizutani;H. Nakanishi;Yong Nan Li;Hiroki Matsubara;Kosuke Yamamoto;N. Sato;T. Shiraishi;

Visual analog scale questionnaire to assess quality of life specific to each symptom of the international prostate symptom score