A research on a type of motor control by the cerebellum

小脑运动控制类型的研究

• 批准号: 17022033
• 负责人: KITAZAWA Shigeru
• 金额: $ 28.1万
• 依托单位: Juntendo University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research on Priority Areas
• 财政年份: 2005
• 资助国家: 日本
• 起止时间: 2005 至 2009
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-17022033/
• 关键词: 小脳; 運動制御; 最適化; プルキンエ細胞; 単純スパイク; サッカード; サッケード; 前頭眼野; 補足眼野; 到達運動; BMI; マルチ電極; プリズム順応; 運動学習

We investigated how the cerebellum contributes to the generation of smooth motor commands. For this purpose, we carried out experiments in arm and eye movements. As a result, we showed that simple spike activities recorded from Purkinje cells in the cerebellum encoded dynamics of the arm movements. The results support the hypothesis that the cerebellum optimizes dynamics of the movements. As for eye movements, we estimated onset times, directions and amplitudes of saccadic eye movements from the neural activities recorded from cerebral cortices. We were successful in calculating optimized motor commands to achieve the estimated eye movements.

我们研究了小脑如何有助于产生流畅的运动指令。为此，我们进行了手臂和眼睛运动的实验。结果，我们发现，从小脑浦肯野细胞记录的简单的棘波活动编码了手臂运动的动态。结果支持了小脑优化运动动力学的假说。至于眼球运动，我们根据大脑皮层记录的神经活动来估计眼跳运动的开始时间、方向和幅度。我们成功地计算出了优化的运动指令，以实现估计的眼球运动。

项目成果

Referral of tactile stimuli to action points in virtual reality with reaction force.

通过反作用力将触觉刺激转介到虚拟现实中的动作点。

• 发表时间: 2007
• 期刊: Neuroscience Research 59
• 作者: Moizumi;S.・Yamamoto;S.・Kitazawa;S.
• 通讯作者: S.

Estimating saccade timing and targets from neural activity : Comparison of the macaque frontal eye field and the supplementary eye field

根据神经活动估计扫视时间和目标：猕猴额眼视野和辅助眼视野的比较

• 发表时间: 2008
• 作者: Ohmae;S.;Lu;X.;Uchida;Y.;Takahashi;T.;Nishimori;Y.;Kodaka;Y.;Takashima;I.;Kitazawa S.
• 通讯作者: Kitazawa S.

Neural activity related to reward size and rewarded taiget position in primate supplementary eye field.

与灵长类动物辅助眼野中的奖励大小和奖励目标位置相关的神经活动。

• 发表时间: 2007
• 期刊: Journal of Neuroscience 27
• 作者: Uchida;Y・Lu;X・Ohmae;S・Takahashi;T・Kitazawa;S
• 通讯作者: S

Arrangement of cerebellar interpositus nucleus neurons projecting multisymaptically to primary motor cortex vs prefrontal cortex

小脑间核神经元多症状投射到初级运动皮层与前额叶皮层的排列

• 发表时间: 2007
• 作者: Lu;X・Miyachi;S・Ito;Y・Nambu;S・Kitazawa;S・Takada;M.
• 通讯作者: M.

Neuronal activity in supplementary eye field during a saccadic eye movement task: A correlation between population of timing related neurons and performance level

扫视眼动任务期间辅助眼场的神经元活动：时间相关神经元群体与表现水平之间的相关性

• 发表时间: 2007
• 作者: Ohmae;S.・Lu;X.・Uchida;T.・Takahashi;T.・Kitazawa;S.
• 通讯作者: S.