Effects of perception of environmental sensory stimuli on emotion-related brain functions

我们通过动物模型和人体实验分析了环境刺激感知对神经元应激反应的影响。在动物研究中，白色噪声的再现减弱了下丘脑-垂体-肾上腺轴的室旁神经元激活。在被要求不移动自己身体的参与者的研究中，每分钟的心跳次数在明亮的环境中比在黑暗的环境中显著增加，但不与一些声学刺激的代表。在对腿部康复训练模拟实验的fMRI分析中，在执行训练任务时呈现鸟类歌唱激活了一些与运动相关的大脑区域。虽然，目前，它是很难找到一些动物和人体实验的结果之间的相关性，本研究表明，在动物研究的一些实验范式对人类研究的有用性。

We analyzed an effect of perception of environmental stimuli on neuronal stress response through experiments of animal models and humans. In the animal study, the representation of white noise attenuated paraventricular neuronal activation in the hypothalamic-pituitary-adrenal axis. In the study of participants who were asked not to move their own bodies, the heart beat number per min was significantly increased in bright than in dark environment, but not with the representation of some acoustic stimuli. In the fMRI analysis of a simulation experiment for rehabilitation training of legs, the representation of birds singing while performing the training task activated some emotion-related brain areas in addition to motor-related cortices. Although, at present, it is difficult to find out some correlation between results from the animal and human experiments, the present study suggests the usefulness of some experimental paradigms in the animal study for the human study.