Search for polymorphisms of genes regulating population-specific morphological traits and functional analyses
Search for polymorphisms of genes regulating population-specific morphological traits and functional analyses
批准号:
21249046
负责人:
KODA Yoshiro
金额:
$19.22万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (A)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011
中文摘要
在形态学领域,对指纹、肤色等易观察的形态学特征进行了研究。近年来的研究表明,许多基因以群体特异性的方式调控性状。本研究利用全基因组多态性阵列技术,寻找决定十个手指嵴总数的基因多态性。此外,我们开发了一种基于FOXP2(叉头盒P2)的方法来区分人类动物起源,FOXP2参与人类的语音和语言发育。
英文摘要
The easily-observed morphological traits such as fingerprints and skin colors had been studied in morphologic field. Recent studies suggest that many genes are responsible for regulation of traits with population-specific manner. In this study, we searched for polymorphisms of genes determining the total ridge counts of ten fingers by genome-wide polymorphism array technique. In addition, we developed a method to distinguish human animal origin based on FOXP2(forkhead box P2) that is involved in speech and language development in humans.
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LAMP法を用いた輸血副作用原因遺伝子ハプトグロビン欠失アリルの検出
使用 LAMP 方法检测触珠蛋白缺失等位基因(负责输血副作用的基因)
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[副島美貴子, 神田芳郎]
通讯作者:
神田芳郎
Functional and genetic survey of all known single-nucleotide polymorphisms within the human deoxyribonuclease I gene in wide-ranging ethnic groups
对广泛种族群体中人类脱氧核糖核酸酶 I 基因内所有已知单核苷酸多态性的功能和遗传调查
DOI:
--
发表时间:
2011
期刊:
DNA Cell Biol
影响因子:
3.1
作者:
[Fujihara J, Ueki M, Yasuda T, Iida R, Soejima M, Koda Y, Kimura-Kataoka K, Kato H, Panduro A, Tongu M, Takesshita H]
通讯作者:
Takesshita H
A biochemical and genetic study on all non-synonymous single nucleotide polymorphisms of the gene encoding human deoxyribonuclease I potentially relevant to autoimmunity
对可能与自身免疫相关的人脱氧核糖核酸酶 I 编码基因的所有非同义单核苷酸多态性的生化和遗传学研究
DOI:
10.1016/j.biocel.2010.04.012
发表时间:
2010
期刊:
Int J Biochem Cell Biol.
影响因子:
--
作者:
[Yasuda T, Ueki M, Takeshita H, Fujihara J, Kimura-Kataoka K, Iida R, Tsubota E, Soejima M, Koda Y, Kato H, Panduro A]
通讯作者:
Panduro A
心筋に広範な収縮帯壊死を認めた小児虐待の一剖検例
虐童尸检显示心肌大面积收缩区坏死
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[神田芳郎, 副島美貴子]
通讯作者:
副島美貴子
FDistribution of 42-bp variable tandem repeat polymorphism of the cold-induced autoinflammatory syndrome I (CIASI) gene in eight human populations.
F 寒冷诱导自身炎症综合征 I (CIASI) 基因的 42 bp 可变串联重复多态性在八个人群中的分布。
DOI:
--
发表时间:
2011
期刊:
Leg Med (Tokyo)
影响因子:
--
作者:
[Omi T, Koda Y, Soejima M, Munkhtulga L, Iwamoto S.]
通讯作者:
Iwamoto S.
共 30 条
Development of assay system of biochemical markers by TaqMan protein quantification method useful for forensic diagnosis.
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批准号:23659373
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.41万
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财政年份:2011
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负责人:KODA Yoshiro
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依托单位:
Haplotype analysis of polymorphic genes and its forensic application
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批准号:16390197
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$4.8万
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财政年份:2004
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负责人:KODA Yoshiro
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依托单位:
Analyses of SNPs on various human gene loci and their forensic applications
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批准号:13670440
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.37万
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财政年份:2001
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负责人:KODA Yoshiro
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依托单位:
Analysis of the DNA sequence variation of the fucosyltransferase genes
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批准号:11670429
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.05万
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财政年份:1999
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负责人:KODA Yoshiro
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依托单位: