New Efficient Alkyne Cyclization Strategies for Complex Molecule Synthesis

用于复杂分子合成的新型高效炔烃环化策略

• 批准号: DP160101682
• 负责人: Prof Philip Chan
• 金额: $ 35.01万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2016
• 资助国家: 澳大利亚
• 起止时间: 2016-01-01 至 2019-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP160101682
• 关键词: New; Efficient; Alkyne; Cyclization; Strategies

The project aims to realise new selective and efficient alkyne cyclisation strategies to the carbocyclic and heterocyclic family of compounds, which have wide synthetic, biological and materials applications. This would be demonstrated by identifying new green and sustainable synthetic methods based on minimising and/or eliminating the consumption of various material and energy resources and chemical waste production. The newly developed catalytic methodologies would serve as new synthetic tools that would inform current thinking in organic chemistry and contribute new and efficient conceptual chemical processes to academic, chemical and pharmaceutical communities.

该项目旨在实现碳环和杂环化合物家族的新的选择性和有效的炔环化策略，这些化合物具有广泛的合成，生物和材料应用。这将通过确定新的绿色和可持续的合成方法来证明，该方法基于最小化和/或消除各种材料和能源的消耗以及化学废物的产生。新开发的催化方法将作为新的合成工具，为有机化学的当前思维提供信息，并为学术界、化学界和制药界提供新的有效的概念化学过程。