New Efficient Alkyne Cyclization Strategies for Complex Molecule Synthesis

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The project aims to realise new selective and efficient alkyne cyclisation strategies to the carbocyclic and heterocyclic family of compounds, which have wide synthetic, biological and materials applications. This would be demonstrated by identifying new green and sustainable synthetic methods based on minimising and/or eliminating the consumption of various material and energy resources and chemical waste production. The newly developed catalytic methodologies would serve as new synthetic tools that would inform current thinking in organic chemistry and contribute new and efficient conceptual chemical processes to academic, chemical and pharmaceutical communities.