hemodynamics of the veno-arterial extracorporeal membrane oxygenation in cardiogenic shock - function and convalescence of the myocardium

本研究的目的是调查和量化VA-ECMO治疗对心源性休克患者的血流动力学影响。为此，在一项随机对照试验中，将对大约40名患者进行住院期间ECMO治疗期间的有创和无创血流动力学测量。要实现的子目标如下：1.)测定不同ECMO流量下的心脏功（压力-容积曲线）。确定住院期间ECMO应用不同阶段的心血管负荷。3.） 与侵入性测量相比，验证3D回声的准确性。

The aim of this study is to investigate and quantify the hemodynamic effects of VA-ECMO therapy in patients in cardiogenic shock. For this purpose, invasive and non-invasive hemodynamic measurements during ECMO therapy during hospitalization will be performed on approximately 40 patients in a randomized controlled trial. The following sub-objectives are to be achieved: 1.) To determine cardiac work (pressure-volume curves) at different ECMO- flow rates 2.) Determination of the cardiovascular workload during different phases of the ECMO application during the hospital stay. 3.) Validation of the accuracy of the 3D echo in comparison to invasive measurements.