hemodynamics of the veno-arterial extracorporeal membrane oxygenation in cardiogenic shock - function and convalescence of the myocardium

心源性休克时静脉-动脉体外膜氧合的血流动力学-心肌功能和恢复期

• 批准号: 517559015
• 负责人: Dr. Christopher Gaisendrees
• 金额: --
• 依托单位: Center for Resuscitation Medicine
• 依托单位国家: 德国
• 项目类别: WBP Fellowship
• 资助国家: 德国
• 项目状态: 未结题
• 来源: https://gepris.dfg.de/gepris/projekt/517559015?language=en
• 关键词: hemodynamics; veno; arterial; extracorporeal; membrane

The aim of this study is to investigate and quantify the hemodynamic effects of VA-ECMO therapy in patients in cardiogenic shock. For this purpose, invasive and non-invasive hemodynamic measurements during ECMO therapy during hospitalization will be performed on approximately 40 patients in a randomized controlled trial. The following sub-objectives are to be achieved: 1.) To determine cardiac work (pressure-volume curves) at different ECMO- flow rates 2.) Determination of the cardiovascular workload during different phases of the ECMO application during the hospital stay. 3.) Validation of the accuracy of the 3D echo in comparison to invasive measurements.

本研究的目的是研究和量化VA-ECMO治疗心源性休克患者的血流动力学效应。为此，在一项随机对照试验中，将在住院期间对大约40名患者进行ECMO治疗期间的侵入性和非侵入性血流动力学测量。要实现以下次级目标：1.)测定不同ECMO流量下的心脏做功(压力-容量曲线)。住院期间ECMO应用不同阶段心血管负荷的测定。3.)与侵入性测量相比较，验证3D回波的准确性。