Molecular mechanisms of differentiation and metastasis of human gastrointestinal cancer stem cells

人胃肠道肿瘤干细胞分化和转移的分子机制

• 批准号: 15K08970
• 负责人: Baba Eishi
• 金额: $ 3.08万
• 依托单位: Kyushu University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2015
• 资助国家: 日本
• 起止时间: 2015-04-01 至 2018-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15K08970/
• 关键词: 大腸癌; 胃癌; 癌幹細胞; 組織幹細胞; オルガノイド; 上皮間葉転換; 印環細胞癌; 消化器癌; スフェア

项目成果

Transition of macrophage to fibroblast promote cancer progression in malignant ascites environment within gastrointestinal peritoneal carcinomatosis patients.

巨噬细胞向成纤维细胞的转变促进胃肠道腹膜癌患者恶性腹水环境中的癌症进展。

• 发表时间: 2016
• 作者: Mamoru Ito;Hiroshi Ariyama;Eishi Baba;et al.
• 通讯作者: et al.

EMT induces sphere forming ability in primary colorectal cancer

EMT 诱导原发性结直肠癌球体形成能力

• 发表时间: 2015
• 作者: Michitaka Nakano;Hiroshi Ariyama;Shingo Tamura;Taichi Isobe;Kohta Miyawaki;Yuta Okumura;Hitoshi Kusaba;Takashi Ueki;Eishi Baba;Koichi Akashi
• 通讯作者: Koichi Akashi

The risk factors for oxaliplatin-induced thrombocytopenia and neuropathy in advanced gastric cancer

奥沙利铂所致进展期胃癌血小板减少和神经病变的危险因素

• 发表时间: 2017
• 作者: Kyoko Inadomi;Hitoshi Kusaba;Akitaka Makiyama;Kenji Mitsugi;Keita Uchino;Shingo Tamura;Yoshihiro Shibata;Taito Esaki;Kenji Tsuchihashi;Shuji Arita;Hiroshi Ariyama;Eishi Baba
• 通讯作者: Eishi Baba

Irinotecan monotherapy as third-line or later treatment in advanced gastric cancer

• DOI: 10.1007/s10120-017-0759-9
• 发表时间: 2018-05-01
• 期刊: GASTRIC CANCER
• 影响因子: 7.4
• 作者: Makiyama, Akitaka;Arimizu, Kohei;Baba, Eishi
• 通讯作者: Baba, Eishi

Efficacy and safety analysis of oxaliplatin-based chemotherapy for advanced gastric cancer with a prior treatment of cisplatin

顺铂治疗晚期胃癌以奥沙利铂为基础化疗的疗效和安全性分析

• 发表时间: 2017
• 期刊: Anticancer Res
• 影响因子: 2
• 作者: Inadomi K;Kusaba H;Matsushita Y;Tanaka R;Mitsugi K;Arimizu K;Hirano G;Makiyama A;Ohmura H;Uchino K;Hanamura F;Shibata Y;Kuwayama M;Esaki T;Takayoshi K;Arita S;Ariyama H;Akashi K;Baba E
• 通讯作者: Baba E