Chest/head circumference ratio at birth and childhood non-alcoholic fatty liver disease

点击翻译按钮获取中文摘要

During the fiscal year, our primary focus was on the recruitment of study participants. Our initial target was to recruit 2500 children; however, due to the outbreak of COVID-19, we were only able to recruit 2190 children, which represents 87.6% of our intended sample size.We successfully collected comprehensive health information from the recruited children, allowing us to gain valuable insights into their overall physical growth and health status. Measurement of height, weight, waist circumference, body fat composition, and blood pressure were taken, providing important data on their physical development.Blood samples were also collected from the participants to analyze a range of biomarkers. Specifically, we measured serum levels of liver enzymes alanine aminotransferase (ALT), aspartate aminotransferase (AST), and gamma-glutamyl transferase (GGT). These enzymes play a crucial role in assessing liver function and can help detect any potential liver disorders, particularly childhood non-alcoholic fatty liver disease (NAFLD). In addition to liver enzymes, we analyzed lipids (triglycerides, total cholesterol, HDL cholesterol, LDL cholesterol), HbA1c, adiponectin, uric acid, creatinine, and hs-CRP as these markers offer valuable information related to metabolic health and provide insights into the risk of developing cardio-metabolic disorders.