Genetical, physiological and ecological studies on the mechanisms of insecticide resistance.

在褐飞虱（Nilaparvata legens）中，发现马拉硫磷与氰戊菊酯存在负相关交叉抗性。在马拉硫磷和乙氧苯丙之间也发现了类似的现象。在抗马拉硫磷品系中，发现^<14> c -马拉硫磷的表皮渗透减少，^<14> c -马拉硫磷的代谢增强。然而，^<14> c -氰戊酸对神经制剂的表皮渗透、代谢和结合没有差异。小菜蛾（Plutella xylostella）对phenthote的抗性是由于^<14> c - phenthote的表皮渗透性低和乙酰胆碱酯酶对phenthote -oxon的敏感性降低所致。苯甲酸酯的遗传受不完全显性因子控制。小菜蛾对氰戊菊酯的抗性机制是由于^<14> c -氰戊菊酯的表皮渗透降低和神经系统对氰戊菊酯的敏感性降低所致。认为甲氰菊酯抗性遗传受隐性因素和不完全隐性因素控制。

In the brown planthopper, Nilaparvata leugens, the phenomenon of negatively corelated cross resistance was found between malathion and fenvalerate. The similar phenomenon was also found between malathion and ethophenprox. In malathion resistant strain, the cuticular penetration of ^<14>C-malathion was found to be redyced and the metabolism of ^<14>C-malathion was found to be enhanced. However, there were no differences in cuticular penetration, metabolism and binding of ^<14>C-fenvalerate to nerve preparation.In the diamondback moth, Plutella xylostella, phenthoate resistance was found to be caused by low cuticular penetration of ^<14>C-phenthoate and reduced sensitivity of acetylcholinesterase to phenthoate-oxon. Inheritance of phenthoate was controled by an incomplete dominant factor. The resistance mechanism of fenvalerate in the diamondback moth was caused by reduced cuticular penetration of ^<14>C-fenvalerate and reduced sensitivity of nervous system to fenvalerate. The inheritance of fenvalerate resistance was considered to be controled by and imcomplete recessive factor.