The Redox Reaction System of the Iron Porphyrin Complexes.

这项研究的最终目的是了解由铁卟啉络合物组成的氧化还原反应体系，这是生物血红蛋白系统的相关模型。该基金资助的这项为期两年的研究涉及邻位取代芳基卟啉的各种异构体的合成和分离，以及氧化还原反应体系的考察。关于锌卟啉的异构体的报道已作为这项工作的一部分发表。1-3)由于晶体产物的结构研究已经成功。对铁络合物也进行了实验，目前研究的重点是各种吡啶与Fe&lt；(OEP)^&gt；配位的光谱变化。在本研究中，我们观察到当配体分子中含有~CH-NH-基团时，Fe(&lt；III&gt；)还原为Fe(&lt；II&gt；)的反应。关于这项研究的更具体结果将在药品管理局第107次会议上提出。SoC。日本..。

The ultimate purpose of this research in the understanding for the redox reaction system consisting of iron porphyrin complexes which are relevant models for the biological hemoprotein system. The two-year study aided by this fund has involved the synthesis and isolation of various isomers of ortho-substituted arylporphyrin and the survey for the redox reaction system. The reports concerning the atropisomers of zinc porphyrin have been published as the part of this work (ref. 1-3) since the structural study has been successful on the crystal products. Experiments on those of the iron complexes also carried out and the study is now focusing to the the spectral changes on the coordination of various pyridines to Fe <(OEP)^+> . In this study, we observed the reduction reaction of Fe( <III> ) to Fe( <II> ) in the porphyrin when the ligand has the =CH-NH- group in the molecule, e.g. picolylamines. The more specific results on this study will be presented at the 107th meeting of the Pharm. Soc. Jpn..