Studies on lithotripsy with the use of electrohydraulic shock wave and molding of fibrin coaglum for intrhepatic stone.

应用纤维蛋白凝固成型法和液电冲击波碎石术对肝内胆管结石进行了实验和临床研究。1987年，作者用实验性胆道模型，讨论了纤维蛋白凝固物在胆道中的硬度及在不同胆汁和温度条件下的溶解。但是，很难继续这个实验。因为纤维蛋白原的抗原性在临床应用中对人体是有害的。1988年，液电冲击波碎石术在肝内胆管结石患者中试用。从临床试验的结果来看，对于肝内结石复发或残余结石的患者，该方法可以完全破坏各种类型的肝内结石。这种方法安全，无任何麻烦和并发症在操作时。但是，由于病例数量太少，很难得出这种方法在临床上是有用和有效的结论。另一方面，在2例肝内胆管狭窄患者中使用了球囊探条，在这些病例中是有效的。总之，从本研究的结果来看，液电冲击波碎石术和球囊探条扩张治疗肝内胆管结石是有用和有效的，但需要进一步的长期结果和更多的病例来完成本研究。

Experimental and new clinical investigation for intrahepatic stone was studied with the fibrin coaglum molding method and electrohydraulic shock wave lithotripsy. In 1987, rigidity of fibrin coagulum in biliary tract and dissolution on of fibrin coagulum in various conditions of bile juice and temperature was discussed with the experimental biliary tract model. But ,it is difficult to continue this experiment . Because, antigenicity of the fibrinogen is harmful for the human being in the clinical use of them. In 1988, electrohydraulic shock wave lithotripsy in patient with intrahepatic stone was tried to use clinically. From the results of this clinical trials, various types of intrahepatic stone were destroyed completely with this method for the patient of recurrence of intrahepatic stone or remnant stone. This method is safety without any trouble and complication at the time of operation. But, it is difficult to conclude that this method is useful and effective in clinical use, Because the number of this case is too small. On the other hand, balloon bougie for intrahepatic bile duct stricture was used in two cases and it is effective in these cases.In conclusion, from the results of this study, electrohydraulic shock wave lithotripsy and balloon bougie dilation for intrahepatic stone is useful and effective, but further study of long term result and more case is necessary to complete this study.