Fundamental Study of Hydroxy-apatite-coated Metal for Artificial Joint Use.

本研究将羟基磷灰石涂层的SUS 316L不锈钢在负重条件下植入犬股骨内。对种植体-骨界面区进行组织学评价。采用手掌喷涂技术，在SUS 316L不锈钢种植体髓内棒表面涂覆透明质酸。分别于植入后1、3、12个月处死动物，组织学切片显示，3、12个月时，HA涂层种植体顶端与致密的骨小梁直接接触，无纤维组织形成。12个月时，在犬股骨截骨端，HA涂层种植体被厚厚的纤维组织所包围，钛和HA涂层的钛被一种新的技术方法包裹在犬体内。对种植体骨界面的力学强度进行了分析。羟基磷灰石涂层钛骨界面的强度比钛骨界面强。

In the present study, HA coated SUS 316L stainless steel was implanted in canine femur under load-bearing conditions. The implant-bone interface regions were assessed histologically. The intramedullary rod surfaces of SUS 316L stainless steel implants were coated with HA by palsma spraying techniques. The dogs were sacrificed at 1, 3, and 12 months after implantation.Histological sections revealed that the tips of the HA coated implants were in directly contact with dense bony trabecula without any fibrous tissue at 3 and 12 months. While, it was found that HA layer was partially removed in the twelve-month section.On the other hand, the HA coated implant in the osteotomized end of the canine femur was surrounded with thick fibrous tissue at 12 months.Pare titanium and HA coated TI by a new Technique Theremal decomposition method were implanted in canine. The mechamical strength of the implant-bone interface was analysed. The strength of HA coated Ti-bone interface was stroger than that ofti-bone interface.