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Fundamental Study of Hydroxy-apatite-coated Metal for Artificial Joint Use.

人工关节用羟基磷灰石涂层金属的基础研究。

基本信息

批准号：
62570677
负责人：
OKUMURA Shinji
金额：
$ 1.34万
依托单位：
Tokyo Medical and Dental University
依托单位国家：
日本
项目类别：
Grant-in-Aid for General Scientific Research (C)
财政年份：
1987
资助国家：
日本
起止时间：
1987 至 1988
项目状态：
已结题

项目摘要

In the present study, HA coated SUS 316L stainless steel was implanted in canine femur under load-bearing conditions. The implant-bone interface regions were assessed histologically. The intramedullary rod surfaces of SUS 316L stainless steel implants were coated with HA by palsma spraying techniques. The dogs were sacrificed at 1, 3, and 12 months after implantation.Histological sections revealed that the tips of the HA coated implants were in directly contact with dense bony trabecula without any fibrous tissue at 3 and 12 months. While, it was found that HA layer was partially removed in the twelve-month section.On the other hand, the HA coated implant in the osteotomized end of the canine femur was surrounded with thick fibrous tissue at 12 months.Pare titanium and HA coated TI by a new Technique Theremal decomposition method were implanted in canine. The mechamical strength of the implant-bone interface was analysed. The strength of HA coated Ti-bone interface was stroger than that ofti-bone interface.

在本研究中，HA涂层SUS 316L不锈钢在承重条件下植入犬股骨。对种植体-骨界面区域进行组织学评估。采用脉冲喷涂技术对SUS 316L不锈钢种植体髓内杆表面进行HA涂层处理。术后1、3、12个月处死动物，组织学切片显示3、12个月时HA涂层种植体尖端与致密骨小梁直接接触，无任何纤维组织。结果表明：12个月时，HA涂层部分脱落，12个月时，HA涂层种植体周围有较厚的纤维组织，采用热分解法将帕雷和HA涂层钛植入犬体内。分析了种植体-骨界面的力学强度。HA涂层的钛-骨界面强度高于纯钛界面。