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Physical Properties of Tympanic Membrane and Membrane and Membranous Labyrinth

鼓膜、膜和膜迷路的物理性质

基本信息

批准号：
01570964
负责人：
ISHII Tetsuo
金额：
$ 1.41万
依托单位：
Tokyo Women's Medical College
依托单位国家：
日本
项目类别：
Grant-in-Aid for General Scientific Research (C)
财政年份：
1989
资助国家：
日本
起止时间：
1989 至 1991
项目状态：
已结题

项目摘要

The mechanical properties of guinea pig and human tympanic membranes were measured by a microtension tester newly developed by us Guinea pig tympanic membranes were tested under various conditions. When the tensile rate was 4.17X10^<-4>m ・sec^<-1> fresh specimens were 8.8 times stronger for a tension appllied parallel to the radial fibers than for that applied at a right angle to the them No difference in tensile strength was seen when the tension was applied at a right angle to the radial fibers. When the tensile direction was parallel to the radial fibers, the posterior part was stronger than the anterior part. Two human tympanic membranes were measured under formalin fixation. The measured values were calculated into those of the fresh specimens based on the results of the guinea pig material. The adjusted values for fresh human specimens were 2.56 kgf . mm^<-2> at a right angle to the radial fibers and 3, 28 kgf . mm^<-2> parallel to them Applying the thin cylinder and shell theory, the breakage pressure of the human tympanic membrane was calculated to be 1.00-22.4 atmospheric pressure.Mechanical properties of the semicircular canals of guinea pig, frogs and water fishes, and of human membranous labyrinths were tested. Tensile strength of the semicircular canals of guinea pig frog and water fish was greater in the order of guinea pig frog and fish, In the human membranous labyrinth the saccular membrane was the weakest, followed by Reissner's membrane, the utricular membrane and the semicircular canal. These values were converted form tensile strength to breakage pressure. The breakage pressure of the saccular membrane was 64.0 mmHg

用自行研制的微张力仪测定了豚鼠和人鼓膜的力学性能，并在不同条件下对豚鼠鼓膜进行了测试。当拉伸速率为4.17×10~(-4)时，平行于径向纤维的拉伸强度是与径向纤维成直角的拉伸强度的8.8倍，与径向纤维成直角的拉伸强度没有差异。当拉伸方向与放射状纤维平行时，后部强于前部。在福尔马林固定下测量了两个人的鼓膜。根据豚鼠材料的结果将测量值计算到新鲜标本的测量值中。新鲜人体标本的调整值为2.56KGF。Mm^&lt；-2；与径向纤维成直角，3，28kgf。用薄壁圆柱壳理论计算出人鼓膜的破裂压力为1.00-22.4大气压，并测试了豚鼠、青蛙、水鱼半规管和人膜迷路的力学性能。豚鼠青蛙和水鱼半规管的抗张强度由大到小依次为豚鼠青蛙和鱼类，人膜迷路中球囊膜最弱，其次是Reissner膜、椭圆膜和半规管。这些值从抗拉强度转换为断裂压力。球囊膜破裂压为64.0毫米汞柱