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Hyperthermia System with Re-Entrant Cavity Applicator for Deep Seated Tumor.

带有用于深部肿瘤的凹腔施药器的热疗系统。

基本信息

批准号：
01870047
负责人：
SAITOH Yoshiaki
金额：
$ 10.62万
依托单位：
Niigata University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Developmental Scientific Research (B).
财政年份：
1989
资助国家：
日本
起止时间：
1989 至 1990
项目状态：
已结题

项目摘要

For treatment of deep seated tumor a hyperthermia system with re-entrant cavity resonator was developed.1. We confirmed concentrated heating for 8 cm thickness phantom was possible.2. We fabricated a larger re-entrant cavity resonator for 15 cm thickness phantom but heating the center of the phantom was resulted in failure. To solve this problem two metal disks (field concentrating devices) were attached on the phantom. This method brought excellent results of concentrated heating.3. Two types of heating pattern : one is cylindrical and the other is global. We established a method of determining a frequency to obtain cylindrical heating pattern at all times, but the global heating pattern may be realized with further research. All results are taken from the thermo-camera.4. Through numerical analysis with finite element method it is also confirmed the heating method with re-entrant cavity resonator applicator is superior to the usual RF heating method. Especially the heating method with the re-entrant cavity resonator applicator having two field concentrating devicesmay serve to heat deep seated tumor.5. The following themes must be examined : 1) In order to heat a 25 cm thickness phantom of similar clinical condition a larger re-entrant cavity applicator must be developed and heating pattern must be measured. 2) A elaborate phantom with similar electric coefficient and structure as human body must be introduced to evaluate the heating characteristics.

为治疗深部肿瘤，研制了一种再入腔腔腔热疗系统。我们确认对厚度为8 cm的模体进行集中加热是可行的。我们制作了一个更大的重入腔谐振器，用于15cm厚度的模体，但由于加热模体中心导致失败。为了解决这一问题，我们将两个金属圆盘（场聚焦装置）附着在假体上。该方法取得了较好的集中加热效果。两种加热模式：一种是圆柱形的，另一种是全球的。我们建立了一种确定频率的方法，可以在任何时候获得圆柱形的加热模式，但进一步的研究可以实现全局的加热模式。所有结果均来自热成像仪。通过有限元数值分析，也证实了再入腔式谐振器加热器加热方法优于常规射频加热方法。特别是具有两个场聚焦装置的再入腔谐振器的加热方法可以用于加热深部肿瘤。必须检查以下主题：1)为了加热25厘米厚的类似临床条件的假体，必须开发一个更大的再入腔涂抹器，并且必须测量加热模式。2)必须引入与人体相似的电系数和结构的精细模型来评估其加热特性。