Distribution Mechanism of Transport Materials in the neurons.

脊椎动物神经元有轴突和树突两种明确的突起，它们需要不同的功能材料进行传递和接收，但不含合成材料的细胞器。该材料将在神经元体细胞内质网和高尔基体合成，并分布于轴突和树突。这两个过程的分布机制已经从形态学的角度进行了研究。1)项目第一年：发现金鱼浦肯野细胞质具有尼氏体外缘和中央高尔基区，一束轴突微管深入高尔基区。2)第二年：用连续超薄切片重建10个神经元，研究轴突微管束与高尔基网络的三维关系。3)第三年：在系列超薄切片上重建浦肯野细胞树突中包含的光滑内质网层状堆叠，并报道了IP3受体的定位。因此，可以说每个神经元都处于不同的功能状态，神经元细胞器的三维结构很难用一个简单的规则来调节。

Vertebrate neurons regularity have two definite kinds of processes, axon and dendrites, both of which need different functional materials for transmission and reception, but contain no organelles for synthesis of materials. The materials will be synthesized in ER and Golgi apparatus of neuronal soma and distributed for the axon and dendrites. The mechanism of distribution for both processes has been examined in the morphological viewpoint.1) First project year: It was revealed that goldfish Purkinje cell cytoplasm has a peripheral rim of Nissl body and a central Golgi area, and a bundle of axonal microtubules penetrates deeply into the Golgi area.2) Second year: Three-dimensional relationships between the bundle of axonal microtubules and the Golgi networks were examined in 10 neurons reconstructed from serial ultrathin sections.3) Third year: Lamellar stacks of smooth endoplasmic reticulum contained in the Purkinje cell dendrites and in which the localization of IP3 receptors is reported, were reconstructed from the serial ultrathin sections.As a result, it can be said that each neuron is in various functional state and it is difficult for three-dimensional architecture of neuronal organelles to regulate in a simple rule.