DEVELOPMENT OF NEW CHIRAL CATALYSTS

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The metal complex is very important in the homogeneous asymmetric catalytic reaction. Accordingly, new chiral metal complexes as catalyst was synthesized.Cobalt halogen complexes of composition CoX_2(L-L) containing different bidentate phosphine ligands (BINAP, DIOP, and CHIRAPHOS) have been prepared and characterized. The [CoX_2P] complexes were obtained from the reaction of CoCl_3ﾟ6H_2O with 1 equiv. of bidentate phosphine ligands in CH_2Cl_2. ^<31>P NMR spectrum of this complex showed a singlet at -14.79 ppm. ^<31>P NMR chemical shift for the cobalt halogen complex depend on the ligated phosphine. The chemical shift is very close to the BINAP ligand. The structures of [CoCl_2(binap)] is determined by X ray crystallography : for [CoCl_2(binap)], C_<45>H_<34>P_2Cl_4Co, monoclinic, P2_1, a=10.870(4) A, b=13.024(4)A^^ﾟ, C=14.316(3)A^^ﾟ, beta=99.14(2)ﾟ, V=2001(1)A^^ﾟ^3, Z=2, R(F)=4.5%. This compound is very stable and melts without decomposition at 245-250 ﾟC. Other related complexes have also been prepared and characterized.Nickel halogen complex of composition NiX_2(L-L) containing bidentate phosphine ligand (BINAP) have also been prepared.No using the initial catalyst for the asymmetric hydrogenation, perfluoroalkylation, and closs coupling reaction have been provided good results.