Research of Totally Implantable Linear Pulse Motor-Driven Artificial Heart

完全可植入直线型人工心脏的动物实验本课题组一直在考虑用直线脉冲电机（LPM）作为驱动源的可能性，并研制了一系列带有该电机的人工心脏模型。新研制的可植入直线型人工心脏（LAH）有两个血泵，由LPM交替充放气，导致推板使血液脉动LAH直径为85 mm，宽为95 mm（总体积为0.55升），重1.2 kg。LPM包括作为次级构件的扁平动子和作为初级构件的两个定子。两个线性轴承用于支撑它们。定子和动子都是由具有高饱和磁通密度的层压薄层Permendur制成。LPM在每分钟60-100次跳动时提供50-60牛顿的动力推力，采用Windkessel型模拟循环系统对LAH的性能进行了评价，结果表明，LAH能够满足人体静止时的流速要求。获得的最大主动脉压（AoP max）为141 mmHg，最大肺动脉压（PAP max）为28 mmHg，最大流速为5.1 L/min。1993年9月24日，与广岛大学医学院合作，使用绵羊进行了动物试验。实验证实，植入的人工心脏在活体中可以发挥预期的功能。心脏正常工作长达两个小时在设备能够应用于临床之前，开发项目仍然面临着许多未解决的问题，但它一直在朝着最终目标稳步前进

Totally lmplantable Linear-type Artificial Heart under Animal TestingOur group has been considering the possibility of using a linear pulse motor (LPM) as a driving source, and has developed a series of artificial heart models with the motorThe newly developed implantable linear-type artificial heart (LAH) has two blood pumps, which are inflated and deflated by the LPM alternately, causing a pusher plates to pulsate the bloodThe LAH measures 85 mm in diameter * 95mm wide (0.55 litters total volume) , and weighs 1.2kg. The LPM comprises a flat mover as the secondary member and two stators as the primary member. Two linear bearings are used to support them. Both stators and mover are made of laminated thin layrs of Permendur with high saturation flux density.The LPM provides a kinetic thrust of 50-60 newtons at 60-100 beats per min., the speed required by an artificial heartA Windkessel-type mock circulatory system was used to evaluate the performance of the LAH.The results were good enough to meet the flow rate requirements of a human at rest. Maximum aortic pressure (AoP max) of 141 mmHg, maximum pulmonary arterial pressure (PAP max) of 28 mmHg, and maximum flow rate of 5.1 liters per min. were obtainedIn collaboration with Hiroshima University Medical School, animal testing using a sheep was conducted on September 24 1993. The experiment confimed that the implanted artificial heart could function as expected in a living body. The heart worked properly for up to two hoursThe development profect still faces a number of unsolved problems before device can be applied clinically, but it has been steadily advancing toward the final target