Integrative studies on acclimatization mechanism to extreme altitude hypoxia in Himalayan areas - A joint project of Kyoto and Chida University

对巴基斯坦罕萨地区的老年功能评估和社会文化调查进行了研究。罕萨75岁以上老年人神经行为功能评分高于日本老年人。虽然日本女性老年人的健康水平高于男性老年人，但罕萨男性老年人的健康水平高于女性老年人。通过视觉模拟量表评估的主观幸福感得分，罕萨女性老年人显著低于罕萨男性老年人或日本老年人。年龄和收缩压之间的相关性是不同的那些村庄在Hunzaarea.Geriatric功能评估和社会文化调查也进行了调查，在厄瓜多尔的比尔卡班巴，这是已知的长寿的人，以及Hunza地区。Vilcabamba、Hunza和日本的神经行为功能各指标得分均与年龄显著相关，表明我们采用的各项指标均适用于老年功能的评定方法。比尔卡班巴老年人的神经行为功能评分并不高于日本老年人。结果表明，Vilcabamba地区老年人的主观健康、经济状况和幸福感得分低于日本，安第斯地区儿童的老年功能评定、发育里程碑和心血管疾病危险因素也低于日本，生物学衰老和发育不仅受遗传因素的影响，还受社会文化生活方式的影响。

Geriatric functional assessment and socio-cultural survey in Hunza in Pakistan were investigated. The scores in neurobehavioral functions in the older elderly (over 75 year-old)in Hunza were higher than the older elderly in Japan. Al though the female elderly were healthier than the male one in Japan, the male elderly were healthier than the female one in Hunza. The scores in subjective happiness evaluated by visual analogue scale was significantly lower in the female elderly in Hunza than in the male elderly in Hunza or Japan elderly population. The correlation between age and systolic blood pressure was different among the villages in Hunza area.Geriatric functional assessment and socio-cultural survey was investigated also in Vilcabamba in Equador which was known to be the area of long-living people, as well as Hunza. The scores in each index of neurobehavioral functions were significantly correlated with age in Vilcabamba as well as in Hunza and in Japan, indicating that each indices we adopted was suitable to the method to assess the geriatric functions. The scores in neurobehavioral functions in the older elderly in Vilcabamba were not higher than those in Japan. The scores in subjective healthiness, economical condition and happiness were lower in the elderly in Vilcabamba than in ones in Japan.As well as geriatric functional assessment, development milestone and risk factors for cardiovascular diseases in children in Andean area were also investigated.Both biological aging and development were suggested to be influenced by not only genetic factors but also socio-cultural life style.